Structural basis for inhibition of cyclin-dependent kinase 9 by flavopiridol (Q44020898)

29 November 2017

Structural basis for inhibition of cyclin-dependent kinase 9 by flavopiridol (English)

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29 November 2017

Walter Filgueira de Azevedo

series ordinal

1

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29 November 2017

Fernanda Canduri

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2

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29 November 2017

Nelson José Freitas da Silveira

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3

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29 November 2017

language of work or name

English

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publication date

1 April 2002

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Biochemical and Biophysical Research Communications

29 November 2017

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29 November 2017

293

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29 November 2017

1

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29 November 2017

566-571

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Animal cell cycles and their control

29 November 2017

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Activation of human cyclin-dependent kinases in vitro

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Human cDNAs encoding homologs of the small p34Cdc28/Cdc2-associated protein of Saccharomyces cerevisiae and Schizosaccharomyces pombe

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Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.

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Flavopiridol inhibits P-TEFb and blocks HIV-1 replication

7 January 2021

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Preclinical and clinical development of cyclin-dependent kinase modulators

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Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors

7 January 2021

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Prediction of the three-dimensional structure of human interleukin-7 by homology modeling.

7 January 2021

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Knowledge-based prediction of protein structures and the design of novel molecules

7 January 2021

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18th Sir Hans Krebs lecture. Knowledge-based protein modelling and design

7 January 2021

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Comparative protein modelling by satisfaction of spatial restraints

7 January 2021

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Derivation of rules for comparative protein modeling from a database of protein structure alignments

7 January 2021

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Evaluation of comparative protein modeling by MODELLER

7 January 2021

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Modelling mutations and homologous proteins

7 January 2021

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Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site

7 January 2021

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CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

7 January 2021

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Calculation of protein conformations by proton-proton distance constraints. A new efficient algorithm

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The CCP4 suite: programs for protein crystallography

7 January 2021

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Crystal structure of cyclin-dependent kinase 2

7 January 2021

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Three protein kinase structures define a common motif

7 January 2021

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Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine

7 January 2021

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Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine

7 January 2021

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Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2

7 January 2021

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Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases

7 January 2021

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Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

7 January 2021

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Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles

7 January 2021

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Structure of human uropepsin at 2.45 A resolution

7 January 2021

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Molecular model for the binary complex of uropepsin and pepstatin

7 January 2021

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Structural basis for chemical inhibition of CDK2.

7 January 2021

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

7 January 2021

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

7 January 2021

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Raster3D: photorealistic molecular graphics

7 January 2021

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10.1016/S0006-291X(02)00266-8

7 January 2021

Identifiers

DOI

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29 November 2017

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