Drug interaction studies between paclitaxel (Taxol) and OC144-093--a new modulator of MDR in cancer chemotherapy (Q44027605)

29 November 2017

Drug interaction studies between paclitaxel (Taxol) and OC144-093--a new modulator of MDR in cancer chemotherapy (English)

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29 November 2017

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Emma S Guns

1

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29 November 2017

Tetyana Denyssevych

2

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29 November 2017

Ross Dixon

3

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29 November 2017

Marcel B Bally

4

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29 November 2017

Lawrence Mayer

5

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29 November 2017

1 April 2002

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European Journal of Drug Metabolism and Pharmacokinetics

29 November 2017

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29 November 2017

27

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29 November 2017

2

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29 November 2017

119-126

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https://scigraph.springernature.com/pub.10.1007/bf03190426

29 November 2017

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cites work

Assessment of the involvement of CYP3A in the vitro metabolism of a new modulator of MDR in cancer chemotherapy, OC144-193, by human liver microsomes

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https://api.crossref.org/works/10.1007%2FBF03190426

The effects of verapamil and a tiapamil analogue, DMDP, on adriamycin-induced cytotoxicity in P388 adriamycin-resistant and -sensitive leukemia in vitro and in vivo

21 January 2018

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The effect of verapamil on the pharmacokinetics of adriamycin.

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03190426

The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: implications for drug interactions

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03190426

Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833.

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03190426

Tolbutamide 4-hydroxylase activity of human liver microsomes: effect of inhibitors

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03190426

Human liver microsomal metabolism of paclitaxel and drug interactions

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03190426

Variability in human cytochrome P450 paclitaxel metabolism

21 January 2018

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12 December 2020

Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein

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12 December 2020

Hepatic biotransformation of docetaxel (Taxotere) in vitro: involvement of the CYP3A subfamily in humans

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12 December 2020

Modulation and prevention of multidrug resistance by inhibitors of P-glycoprotein

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12 December 2020

The effect of water-soluble vitamin E on cyclosporine pharmacokinetics in healthy volunteers

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12 December 2020

P-glycoprotein expression in human plasma cell myeloma: correlation with prior chemotherapy.

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12 December 2020

Cyclosporin metabolism in human liver microsomes and its inhibition by other drugs

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12 December 2020

The effects of cyclosporine on the pharmacokinetics of doxorubicin in patients with small cell lung cancer.

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12 December 2020

Effects of imidazole derivatives on cytochromes P450 from human hepatocytes in primary culture

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12 December 2020

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

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12 December 2020

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

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12 December 2020

P-glycoproteins and multidrug resistance

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12 December 2020

Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance.

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12 December 2020

SDZ PSC 833, a non-immunosuppressive cyclosporine: its potency in overcoming P-glycoprotein-mediated multidrug resistance of murine leukemia

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12 December 2020

Involvement of human liver cytochrome P450 3A in vinblastine metabolism: drug interactions

1 reference

12 December 2020

The biochemistry of P-glycoprotein-mediated multidrug resistance

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12 December 2020

Reversal of multidrug resistance by verapamil analogues.

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12 December 2020

The multidrug resistance modulator valspodar (PSC 833) is metabolized by human cytochrome P450 3A. Implications for drug-drug interactions and pharmacological activity of the main metabolite.

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12 December 2020

Potentiation of anticancer-drug cytotoxicity by multidrug-resistance chemosensitizers involves alterations in membrane fluidity leading to increased membrane permeability.

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12 December 2020

Phase I pharmacokinetic study of cyclosporin A combined with doxorubicin

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12 December 2020

Identifiers

DOI

10.1007/BF03190426

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29 November 2017

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