Mechanisms involved in stimulation of insulin secretion by the hypoglycaemic alpha-adrenergic antagonist, DG-5128 (Q44030316)

29 November 2017

Mechanisms involved in stimulation of insulin secretion by the hypoglycaemic alpha-adrenergic antagonist, DG-5128 (English)

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

26 October 2022

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

26 October 2022

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

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N. G. Morgan

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1674868

26 October 2022

author name string

S. L. Chan

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1674868

26 October 2022

M. R. Stillings

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26 October 2022

language of work or name

English

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publication date

1 May 1991

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29 November 2017

15 May 1991

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1674868

full work available at URL

26 October 2022

https://api.elsevier.com/content/article/PII:0006291X9190463H?httpAccept=text/xml

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

https://api.elsevier.com/content/article/PII:0006291X9190463H?httpAccept=text/plain

26 October 2022

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Biochemical and Biophysical Research Communications

26 October 2022

published in

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29 November 2017

176

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1545-1551

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The selectivity of DG-5128 as an α2-adrenoceptor antagonist

29 November 2017

2

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Studies of midaglizole (DG-5128). A new type of oral hypoglycemic drug in healthy subjects.

26 October 2022

3

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Initial phase II clinical studies on midaglizole (DG-5128). A new hypoglycemic agent

26 October 2022

4

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Comparative study on the effects of a hypoglycemic 2-substituted-2-imidazoline derivative (DG-5128) and tolbutamide on insulin secretion from and insulin synthesis in the isolated rat pancreatic islets

26 October 2022

6

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Insulin releasing action of 2-[2-(4,5-dihydro-1H-imadazol-2-yl)-1-phenylethyl] pyridine dihydrochloride sesquihydrate (DG-5128), a new, orally effective hypoglycaemic agent

26 October 2022

7

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

A role for alpha-adrenergic receptors in abnormal insulin secretion in diabetes mellitus

26 October 2022

8

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Alpha-adrenergic blockade improves glucose-potentiated insulin secretion in non-insulin-dependent diabetes mellitus

26 October 2022

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Stimulation of insulin secretion by efaroxan may involve interaction with potassium channels

26 October 2022

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

B cell adrenoceptors and sulphonylurea-induced insulin release in mouse islets

26 October 2022

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Phentolamine and yohimbine inhibit ATP-sensitive K+ channels in mouse pancreatic beta-cells

26 October 2022

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Pentitols and insulin release by isolated rat islets of Langerhans

26 October 2022

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Stimulation of insulin secretion from isolated rat islets of Langerhans by melittin

26 October 2022

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Protein phosphorylation is required for diazoxide to open ATP-sensitive potassium channels in insulin (RINm5F) secreting cells

26 October 2022

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Diazoxide and D600 Inhibition of Insulin Release: Distinct Mechanisms Explain the Specificity for Different Stimuli

26 October 2022

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Phentolamine and structurally related compounds selectively antagonize the vascular actions of the K+ channel opener, cromromakalim

26 October 2022

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Rubidium and sodium permeability of the ATP-sensitive K+ channel in single rat pancreatic beta-cells.

26 October 2022

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Properties and functions of ATP-sensitive K-channels

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Dual action of clonidine on insulin release: suppression, but stimulation when alpha 2-adrenoceptors are blocked

26 October 2022

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Are there multiple imidazoline binding sites?

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

[3H]idazoxan binding at non-alpha 2-adrenoceptors in rabbit adipocyte membranes

26 October 2022

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

Alpha 2-adrenoceptor blockade does not enhance glucose-induced insulin release in normal subjects or patients with noninsulin-dependent diabetes

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https://api.crossref.org/works/10.1016/0006-291X(91)90463-H

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Identifiers

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29 November 2017

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