Synthesis and anti-influenza virus activity of 4-guanidino-7-substituted Neu5Ac2en derivatives (Q44061376)

29 November 2017

Synthesis and anti-influenza virus activity of 4-guanidino-7-substituted Neu5Ac2en derivatives (English)

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29 November 2017

Takeshi Honda

1

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29 November 2017

Takeshi Masuda

2

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29 November 2017

Shuku Yoshida

3

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29 November 2017

Masami Arai

4

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29 November 2017

Yoshiyuki Kobayashi

5

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29 November 2017

Makoto Yamashita

6

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29 November 2017

language of work or name

English

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publication date

1 August 2002

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Bioorganic & Medicinal Chemistry Letters

29 November 2017

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29 November 2017

12

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29 November 2017

15

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29 November 2017

1921-1924

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Inhibition of influenza virus replication in tissue culture by 2-deoxy-2,3-dehydro-N-trifluoroacetylneuraminic acid (FANA): mechanism of action

29 November 2017

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Characterization of temperature sensitive influenza virus mutants defective in neuraminidase

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Influenza type A virus neuraminidase does not play a role in viral entry, replication, assembly, or budding

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Rational design of potent sialidase-based inhibitors of influenza virus replication

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7 January 2021

4-Guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid is a highly effective inhibitor both of the sialidase (neuraminidase) and of growth of a wide range of influenza A and B viruses in vitro

1 reference

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7 January 2021

Inhibition of influenza virus replication in mice by GG167 (4-guanidino-2,4-dideoxy-2,3-dehydro-N-acetylneuraminic acid) is consistent with extracellular activity of viral neuraminidase (sialidase)

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7 January 2021

Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity

1 reference

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7 January 2021

Structure-activity relationship studies of novel carbocyclic influenza neuraminidase inhibitors

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7 January 2021

Mechanism of Arthrobacter sialophilus neuraminidase: the binding of substrates and transition-state analogs

1 reference

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7 January 2021

Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 1. Discovery, synthesis, biological activity, and structure-activity relationships of 4-guanidino- and 4-amino-4H-pyran-6-carboxamides

1 reference

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7 January 2021

Chemoenzymatic synthesis of neuraminic acid analogs structurally varied at C-5 and C-9 as potential inhibitors of the sialidase from influenza virus

1 reference

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7 January 2021

Synthesis of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid analogues modified at the C-4 and C-9 positions and their behaviour towards sialidase from influenza virus and pig liver membrane

1 reference

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7 January 2021

Inhibition of sialidases from viral, bacterial and mammalian sources by analogues of 2-deoxy-2,3-didehydro-N-acetylneuraminic acid modified at the C-4 position

1 reference

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7 January 2021

Molecular modeling studies on ligand binding to sialidase from influenza virus and the mechanism of catalysis

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Fluorinated carbohydrates as potential plasma membrane modifiers. Synthesis of 4- and 6-fluoro derivatives of 2-acetamido-2-deoxy-D-hexopyranoses

1 reference

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An efficient process for production of N-acetylneuraminic acid using N-acetylneuraminic acid aldolase.

1 reference

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Chemoenzymatic synthesis of an N-acetylneuraminic acid analogue having a carbamoylmethyl group at C-4 as an inhibitor of sialidase from influenza virus

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900328-1

7 January 2021

10.1016/S0960-894X(02)00328-1

Identifiers

DOI

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29 November 2017

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