Limbic seizures induce P-glycoprotein in rodent brain: functional implications for pharmacoresistance. (Q44066990)

29 November 2017

Limbic seizures induce P-glycoprotein in rodent brain: functional implications for pharmacoresistance (English)

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Annamaria Vezzani

12

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12 May 2020

author name string

Massimo Rizzi

1

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Silvio Caccia

2

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Giovanna Guiso

3

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Cristina Richichi

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Jan A Gorter

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Marisa Aliprandi

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Renzo Bagnati

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Roberto Fanelli

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Rosario Samanin

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Eleonora Aronica

6

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12 May 2020

language of work or name

English

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publication date

1 July 2002

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29 November 2017

Journal of Neuroscience

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volume

22

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issue

14

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page(s)

5833-5839

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describes a project that uses

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ImageQuant

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

P-Glycoprotein on astrocyte foot processes of unfixed isolated human brain capillaries.

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12 December 2020

Induction of P-glycoprotein expression in astrocytes following intracerebroventricular kainate injections.

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Tuberous sclerosis associated with MDR1 gene expression and drug-resistant epilepsy

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Over-expression of P-glycoprotein in malformations of cortical development.

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Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

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Communication between multiple drug binding sites on P-glycoprotein

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Reversal of multidrug resistance by the P-glycoprotein modulator, LY335979, from the bench to the clinic

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Multidrug-resistance protein 1 in focal cortical dysplasia.

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Progression of spontaneous seizures after status epilepticus is associated with mossy fibre sprouting and extensive bilateral loss of hilar parvalbumin and somatostatin-immunoreactive neurons.

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12 December 2020

Carbamazepine is not a substrate for P-glycoprotein

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12 December 2020

P-glycoprotein and multidrug resistance-associated protein are involved in the regulation of extracellular levels of the major antiepileptic drug carbamazepine in the brain

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12 December 2020

Overproduction of voltage-dependent Na+ channels in the developing brain of genetically seizure-susceptible E1 mice

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Increased preproneuropeptide Y mRNA in the rat hippocampus during the development of hippocampal kindling: comparison with the expression of preprosomatostatin mRNA.

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Prognosis of epilepsy in newly referred patients: a multicenter prospective study of the effects of monotherapy on the long-term course of epilepsy. Collaborative Group for the Study of Epilepsy

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Modulation of multidrug resistance by verapamil or mdr1 anti-sense oligodeoxynucleotide does not change the high susceptibility to lymphokine-activated killers in mdr-resistant human carcinoma (LoVo) line.

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MDR1 gene expression and treatment outcome in acute myeloid leukemia.

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Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

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The three mouse multidrug resistance (mdr) genes are expressed in a tissue-specific manner in normal mouse tissues

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Expression of a multidrug resistance gene in human cancers

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Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

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The biochemistry of P-glycoprotein-mediated multidrug resistance

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Mechanisms and clinical significance of multidrug resistance

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Pathophysiological aspects of blood-brain barrier permeability in epileptic seizures

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Early treatment and prognosis of epilepsy

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Modification of seizure activity by electrical stimulation. II. Motor seizure

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Remission of epilepsy: results from the National General Practice Study of Epilepsy.

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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

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The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump

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MDR1 gene expression in brain of patients with medically intractable epilepsy

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Biochemistry of multidrug resistance mediated by the multidrug transporter

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Stereo-electroencephalography methodology: advantages and limits.

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Simultaneous determination of carbamazepine, phenytoin, phenobarbital, primidone and their principal metabolites by high-performance liquid chromatography with photodiode-array detection

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12 December 2020

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

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12 December 2020

Altered brain sodium channel transcript levels in human epilepsy

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12 December 2020

Dose-dependent brain penetration of SDZ PSC 833, a novel multidrug resistance-reversing cyclosporin, in rats

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Animal models of intractable epilepsy

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Cortical dysplasia: an immunocytochemical study of three patients.

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12 December 2020

Effect of the Mdr1a P-glycoprotein gene disruption on the tissue distribution of SDZ PSC 833, a multidrug resistance-reversing agent, in mice.

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Responses of deep entorhinal cortex are epileptiform in an electrogenic rat model of chronic temporal lobe epilepsy

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12 December 2020

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

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12 December 2020

10.1523/JNEUROSCI.22-14-05833.2002

Identifiers

DOI

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12 May 2020

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