Cyclooxygenase 2-dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants (Q44068952)

29 November 2017

Cyclooxygenase 2-dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants (English)

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29 November 2017

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Medora M Hardy

1

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29 November 2017

Karen Seibert

2

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29 November 2017

Pamela T Manning

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29 November 2017

Mark G Currie

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29 November 2017

B Mark Woerner

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29 November 2017

Dorothy Edwards

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29 November 2017

Alane Koki

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29 November 2017

Catherine S Tripp

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29 November 2017

1 July 2002

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29 November 2017

Arthritis & Rheumatology

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29 November 2017

46

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29 November 2017

1789-1803

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29 November 2017

7

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Upregulation of enzymatic activity by interleukin-1 in osteoarthritis

29 November 2017

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The interleukin-1 receptor in normal and osteoarthritic human articular chondrocytes. Identification as the type I receptor and analysis of binding kinetics and biologic function

21 January 2018

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Cytokines in osteoarthritis: mediators or markers of joint destruction?

21 January 2018

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Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2

21 January 2018

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Properties and regulation of cytosolic phospholipase A2.

21 January 2018

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Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

21 January 2018

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Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2

21 January 2018

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Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids.

21 January 2018

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21 January 2018

Cyclooxygenases 1 and 2

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Treatment of osteoarthritis with celecoxib, a cyclooxygenase-2 inhibitor: a randomized controlled trial

21 January 2018

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Cytokine regulation of adult human osteoblast-like cell prostaglandin biosynthesis

21 January 2018

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Prostaglandins: mechanisms of action and regulation of production in bone

21 January 2018

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Prostaglandins and bone: physiology and pathophysiology

21 January 2018

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A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors.

21 January 2018

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Pharmacological analysis of cyclooxygenase-1 in inflammation

21 January 2018

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Potential utility of COX-2 inhibitors in chemoprevention and chemotherapy

21 January 2018

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An improved method for determining proteoglycans synthesized by chondrocytes in culture.

21 January 2018

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Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide.

21 January 2018

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Expression of cyclooxygenase-1 and -2 in rheumatoid arthritis synovium

21 January 2018

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Effects of non-steroidal antiinflammatory drugs and dexamethasone on the activity and expression of matrix metalloproteinase-1, matrix metalloproteinase-3 and tissue inhibitor of metalloproteinases-1 by bovine articular chondrocytes

21 January 2018

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Molecular mechanisms involved in the regulation of prostaglandin biosynthesis by glucocorticoids

21 January 2018

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In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapy

21 January 2018

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In vivo cyclooxygenase expression in synovial tissues of patients with rheumatoid arthritis and osteoarthritis and rats with adjuvant and streptococcal cell wall arthritis.

21 January 2018

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Immunohistochemical localization of prostaglandin e in rheumatoid synovial tissues

21 January 2018

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The effect of naproxen and interleukin-1 on proteoglycan catabolism and on neutral metalloproteinase activity in normal articular cartilage in vitro.

21 January 2018

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Effects of meloxicam, compared with other NSAIDs, on cartilage proteoglycan metabolism, synovial prostaglandin E2, and production of interleukins 1, 6 and 8, in human and porcine explants in organ culture.

21 January 2018

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Nitric oxide synthase and cyclooxygenases: distribution, regulation, and intervention in arthritis.

21 January 2018

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Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets

21 January 2018

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Matrix metalloproteinases: a review

21 January 2018

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Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints

21 January 2018

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Preferential mRNA expression of prostromelysin relative to procollagenase and in situ localization in human articular cartilage

21 January 2018

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Stimulation of prostaglandin E2 production by interleukin-1 alpha and transforming growth factor alpha in osteoblastic MC3T3-E1 cells

21 January 2018

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Regulation of prostaglandin G/H synthase-2 expression by interleukin-1 in human osteoblast-like cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ART.10356

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29 November 2017

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