SAR of 2,6-diamino-3,5-difluoropyridinyl substituted heterocycles as novel p38MAP kinase inhibitors (Q44071155)

29 November 2017

title

SAR of 2,6-diamino-3,5-difluoropyridinyl substituted heterocycles as novel p38MAP kinase inhibitors (English)

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29 November 2017

Laszlo Revesz

1

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29 November 2017

Franco E Di Padova

2

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29 November 2017

Thomas Buhl

3

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29 November 2017

Roland Feifel

4

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29 November 2017

Hermann Gram

5

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29 November 2017

Peter Hiestand

6

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29 November 2017

Ute Manning

7

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29 November 2017

Romain Wolf

8

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29 November 2017

Alfred G Zimmerlin

9

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29 November 2017

language of work or name

English

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publication date

1 August 2002

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Bioorganic & Medicinal Chemistry Letters

29 November 2017

published in

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29 November 2017

volume

12

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29 November 2017

issue

16

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29 November 2017

page(s)

2109-2112

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p38 MAP kinase: molecular target for the inhibition of pro-inflammatory cytokines.

29 November 2017

cites work

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7 January 2021

Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles

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7 January 2021

Induction of cyclo-oxygenase-2 expression by methyl arachidonyl fluorophosphonate in murine J774 macrophages: roles of protein kinase C, ERKs and p38 MAPK

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7 January 2021

SAR of 4-hydroxypiperidine and hydroxyalkyl substituted heterocycles as novel p38 map kinase inhibitors

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https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900336-0

7 January 2021

General Method for Synthesis of Bipyridines: Palladium Catalyzed Cross-coupling Reaction of Trimethylstannyl-pyridines with Bromopyridines

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7 January 2021

Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds

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https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900336-0

7 January 2021

The Palladium-Catalyzed Cross-Coupling Reactions of Organotin Reagents with Organic Electrophiles[New Synthetic Methods(58)]

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7 January 2021

Binding mode of the 4-anilinoquinazoline class of protein kinase inhibitor: X-ray crystallographic studies of 4-anilinoquinazolines bound to cyclin-dependent kinase 2 and p38 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900336-0

7 January 2021

Molecular basis for p38 protein kinase inhibitor specificity

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https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900336-0

7 January 2021

Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase

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https://api.crossref.org/works/10.1016%2FS0960-894X%2802%2900336-0

7 January 2021

Pyrimidinylimidazole inhibitors of CSBP/p38 kinase demonstrating decreased inhibition of hepatic cytochrome P450 enzymes.

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7 January 2021

Microtiter plate assays for inhibition of human, drug-metabolizing cytochromes P450

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7 January 2021

10.1016/S0960-894X(02)00336-0

Identifiers

DOI

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29 November 2017

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