Targeted depletion of lymphotoxin-alpha-expressing TH1 and TH17 cells inhibits autoimmune disease (Q44118287)

30 November 2017

Targeted depletion of lymphotoxin-alpha-expressing TH1 and TH17 cells inhibits autoimmune disease (English)

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30 November 2017

Eugene Y Chiang

1

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30 November 2017

Ganesh A Kolumam

2

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30 November 2017

Xin Yu

3

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30 November 2017

Michelle Francesco

4

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30 November 2017

Sinisa Ivelja

5

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30 November 2017

Ivan Peng

6

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30 November 2017

Peter Gribling

7

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30 November 2017

Jean Shu

8

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30 November 2017

Wyne P Lee

9

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30 November 2017

Canio J Refino

10

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30 November 2017

Mercedesz Balazs

11

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30 November 2017

Andres Paler-Martinez

12

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30 November 2017

Allen Nguyen

13

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30 November 2017

Judy Young

14

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30 November 2017

Kai H Barck

15

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30 November 2017

Richard A D Carano

16

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30 November 2017

Ron Ferrando

17

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30 November 2017

Lauri Diehl

18

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30 November 2017

Devavani Chatterjea

19

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30 November 2017

Jane L Grogan

20

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30 November 2017

language of work or name

English

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publication date

28 June 2009

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30 November 2017

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30 November 2017

15

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30 November 2017

766-773

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30 November 2017

7

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https://scigraph.springernature.com/pub.10.1038/nm.1984

30 November 2017

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cites work

Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion

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Effect of targeted disruption of STAT4 and STAT6 on the induction of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

Cutting edge: Th1 cells facilitate the entry of Th17 cells to the central nervous system during experimental autoimmune encephalomyelitis

21 January 2018

1 reference

A role for the lymphotoxin/LIGHT axis in the pathogenesis of murine collagen-induced arthritis.

21 January 2018

1 reference

A role for surface lymphotoxin in experimental autoimmune encephalomyelitis independent of LIGHT.

21 January 2018

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IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

12 December 2020

Lymphotoxin but not tumor necrosis factor functions to maintain splenic architecture and humoral responsiveness in adult mice

1 reference

12 December 2020

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

1 reference

12 December 2020

Even though T-cell-directed trials have been of limited success, is there reason for optimism?

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12 December 2020

B cell-deficient mice do not develop type II collagen-induced arthritis (CIA)

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12 December 2020

Dissecting the role of lymphotoxin in lymphoid organs by conditional targeting

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12 December 2020

Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17

1 reference

12 December 2020

Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

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12 December 2020

Both the lymphotoxin and tumor necrosis factor pathways are involved in experimental murine models of colitis.

1 reference

12 December 2020

IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis

1 reference

12 December 2020

T(H)-17 cells in the circle of immunity and autoimmunity

1 reference

12 December 2020

Ectopic LTαβ Directs Lymphoid Organ Neogenesis with Concomitant Expression of Peripheral Node Addressin and a HEV-restricted Sulfotransferase

1 reference

12 December 2020

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12 December 2020

Lymphoid neogenesis in rheumatoid synovitis

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12 December 2020

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12 December 2020

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

1 reference

12 December 2020

Expression of lymphotoxin-alphabeta on antigen-specific T cells is required for DC function

1 reference

12 December 2020

Novel lymphotoxin alpha (LTalpha) knockout mice with unperturbed tumor necrosis factor expression: reassessing LTalpha biological functions.

1 reference

12 December 2020

Blockade of lymphotoxin pathway exacerbates autoimmune arthritis by enhancing the Th1 response

1 reference

12 December 2020

An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease.

1 reference

12 December 2020

Interleukin-17 in fashion, at last: ten years after its description, its cellular source has been identified

1 reference

12 December 2020

B-cell depletion inhibits arthritis in a collagen-induced arthritis (CIA) model, but does not adversely affect humoral responses in a respiratory syncytial virus (RSV) vaccination model

1 reference

12 December 2020

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

1 reference

12 December 2020

High resolution mapping of the binding site on human IgG1 for Fc gamma RI, Fc gamma RII, Fc gamma RIII, and FcRn and design of IgG1 variants with improved binding to the Fc gamma R.

1 reference

12 December 2020

In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation

1 reference

12 December 2020

Lymphotoxin/light, lymphoid microenvironments and autoimmune disease

1 reference

12 December 2020

Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice

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12 December 2020

Monoclonal Anti–Interleukin 23 Reverses Active Colitis in a T Cell–Mediated Model in Mice

1 reference

12 December 2020

A shift from adaptive to innate immunity: a potential mechanism of disease progression in multiple sclerosis

1 reference

12 December 2020

Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses

1 reference

12 December 2020

Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data.

1 reference

12 December 2020

Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

1 reference

12 December 2020

Transcription factor T-bet regulates inflammatory arthritis through its function in dendritic cells

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12 December 2020

A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis

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12 December 2020

LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator

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12 December 2020

Expression of surface lymphotoxin and tumor necrosis factor on activated T, B, and natural killer cells

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12 December 2020

B cell immunobiology in disease: evolving concepts from the clinic

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12 December 2020

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

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12 December 2020

Immunopathologic aspects of rheumatoid arthritis: who is the conductor and who plays the immunologic instrument?

1 reference

12 December 2020

Lymphotoxin alphabeta is expressed on recently activated naive and Th1-like CD4 cells but is down-regulated by IL-4 during Th2 differentiation

1 reference

12 December 2020

Overexpression of IL-17 in the knee joint of collagen type II immunized mice promotes collagen arthritis and aggravates joint destruction

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12 December 2020

Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human

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12 December 2020

Blocking lymphotoxin beta receptor signalling exacerbates acute DSS-induced intestinal inflammation--opposite functions for surface lymphotoxin expressed by T and B lymphocytes

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12 December 2020

Network communications: lymphotoxins, LIGHT, and TNF.

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12 December 2020

Identifiers

DOI

10.1038/NM.1984

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release_twaheubmdbhj5gn2clmerbsjuu

30 November 2017

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Fatcat

https://api.fatcat.wiki/v0/release/twaheubmdbhj5gn2clmerbsjuu

24 November 2022

mapped directly with Wikidata item

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