Rheb is in a high activation state and inhibits B-Raf kinase in mammalian cells (Q44127157)

30 November 2017

Rheb is in a high activation state and inhibits B-Raf kinase in mammalian cells (English)

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30 November 2017

Edward Im

1

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30 November 2017

Friederike C von Lintig

2

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30 November 2017

Jeffrey Chen

3

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30 November 2017

Shunhui Zhuang

4

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30 November 2017

Wansong Qui

5

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30 November 2017

Shoaib Chowdhury

6

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30 November 2017

Paul F Worley

7

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30 November 2017

Gerry R Boss

8

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30 November 2017

Renate B Pilz

9

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30 November 2017

language of work or name

English

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publication date

1 September 2002

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30 November 2017

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30 November 2017

21

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30 November 2017

6356-6365

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30 November 2017

41

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205792

30 November 2017

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1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205792

The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product.

21 January 2018

1 reference

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Increasing complexity of Ras signaling.

21 January 2018

1 reference

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21 January 2018

1 reference

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Activation of the Rap1 guanine nucleotide exchange gene, CalDAG-GEF I, in BXH-2 murine myeloid leukemia

21 January 2018

1 reference

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A novel approach for expression cloning of small GTPases: identification, tissue distribution and chromosome mapping of the human homolog of rheb

21 January 2018

1 reference

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Internalized epidermal growth factor receptors participate in the activation of p21(ras) in fibroblasts

21 January 2018

1 reference

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The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205792

Ras-induced activation of Raf-1 is dependent on tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205792

Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death

21 January 2018

1 reference

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Differential regulation of Raf-1, A-Raf, and B-Raf by oncogenic ras and tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205792

Negative regulation of Raf-1 by phosphorylation of serine 621.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205792

Isolation of cDNA and genomic clones of a human Ras-related GTP-binding protein gene and its chromosomal localization to the long arm of chromosome 7, 7q36

21 January 2018

1 reference

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Association of MEK1 with p21ras.GMPPNP is dependent on B-Raf

21 January 2018

1 reference

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Modulation of kinase activity and oncogenic properties by alternative splicing reveals a novel regulatory mechanism for B-Raf

21 January 2018

1 reference

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Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway

21 January 2018

1 reference

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Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells

21 January 2018

1 reference

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Cell type-specific regulation of B-Raf kinase by cAMP and 14-3-3 proteins

21 January 2018

1 reference

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Biochemical characterization of baculovirus-expressed rap1A/Krev-1 and its regulation by GTPase-activating proteins

21 January 2018

1 reference

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Biochemical Analysis of MEK Activation in NIH3T3 Fibroblasts

21 January 2018

1 reference

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The Ras branch of small GTPases: Ras family members don't fall far from the tree

21 January 2018

1 reference

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Accumulation of p21ras.GTP in response to stimulation with epidermal growth factor and oncogene products with tyrosine kinase activity

21 January 2018

1 reference

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Platelet-derived growth factor stimulates formation of active p21ras.GTP complex in Swiss mouse 3T3 cells

21 January 2018

1 reference

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Determination of absolute amounts of GDP and GTP bound to Ras in mammalian cells: comparison of parental and Ras-overproducing NIH 3T3 fibroblasts

21 January 2018

1 reference

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Inhibition of phosphatidylinositol 3-kinase activity by adenovirus-mediated gene transfer and its effect on insulin action

21 January 2018

1 reference

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Cyclic-GMP-dependent protein kinase inhibits the Ras/Mitogen-activated protein kinase pathway

21 January 2018

1 reference

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Ras signaling in the inner medullary cell response to urea and NaCl

21 January 2018

1 reference

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Characterization of Rheb functions using yeast and mammalian systems

21 January 2018

1 reference

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The Saccharomyces cerevisiae Rheb G-protein is involved in regulating canavanine resistance and arginine uptake

21 January 2018

1 reference

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Quantitative determination of Rap 1 activation in cyclic nucleotide-treated HL-60 leukemic cells: lack of Rap 1 activation in variant cells

21 January 2018

1 reference

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cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205792

Multiple Ras functions can contribute to mammalian cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205792

Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals

21 January 2018

1 reference

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Different effects of various phospholipids on Ki-Ras-, Ha-Ras-, and Rap1B-induced B-Raf activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205792

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1205792

1 reference

30 November 2017

1 reference