Replacement of active-site cysteine-436 by serine converts cytochrome P450 2B4 into an NADPH oxidase with negligible monooxygenase activity (Q44141003)

30 November 2017

title

Replacement of active-site cysteine-436 by serine converts cytochrome P450 2B4 into an NADPH oxidase with negligible monooxygenase activity (English)

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30 November 2017

Kostas P Vatsis

1

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30 November 2017

Hwei-Ming Peng

series ordinal

2

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30 November 2017

Minor J Coon

series ordinal

3

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30 November 2017

language of work or name

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1 September 2002

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Journal of Inorganic Biochemistry

30 November 2017

published in

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30 November 2017

volume

91

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30 November 2017

issue

4

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30 November 2017

page(s)

542-553

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Heme-Containing Oxygenases

30 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Probing Structure-Function Relations in Heme-Containing Oxygenases and Peroxidases

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

The crystal structure of chloroperoxidase: a heme peroxidase--cytochrome P450 functional hybrid

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Structure of nitric oxide synthase oxygenase dimer with pterin and substrate

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Replacement of the proximal heme thiolate ligand in chloroperoxidase with a histidine residue

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Roles of the proximal heme thiolate ligand in cytochrome p450(cam).

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Site-directed mutageneses of rat liver cytochrome P-450d: axial ligand and heme incorporation

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Proximal cysteine residue is essential for the enzymatic activities of cytochrome P450cam.

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Ipso-substitution by cytochrome P450 with conversion of p-hydroxybenzene derivatives to hydroquinone: evidence for hydroperoxo-iron as the active oxygen species

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Properties of NADPH-cytochrome P-450 reductase purified from rabbit liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Subcellular localization, aggregation state, and catalytic activity of microsomal P450 cytochromes modified in the NH2-terminal region and expressed in Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Peroxo-iron and oxenoid-iron species as alternative oxygenating agents in cytochrome P450-catalyzed reactions: switching by threonine-302 to alanine mutagenesis of cytochrome P450 2B4.

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Purification and properties of a shortened form of cytochrome P-450 2E1: deletion of the NH2-terminal membrane-insertion signal peptide does not alter the catalytic activities

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

On the mechanism of action of cytochrome P450: evaluation of hydrogen abstraction in oxygen-dependent alcohol oxidation

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Hydrogen peroxide in hepatic microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Spectral studies of tert-butyl isothiocyanate-inactivated P450 2E1.

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Structural requirements for the induction of hepatic microsomal cytochrome P450 by imidazole- and pyridine-containing compounds in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Replacement of the proximal histidine iron ligand by a cysteine or tyrosine converts heme oxygenase to an oxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

Mechanism-based inactivation of cytochrome P450 2B4 by aldehydes: relationship to aldehyde deformylation via a peroxyhemiacetal intermediate

1 reference

https://api.crossref.org/works/10.1016%2FS0162-0134%2802%2900438-5

7 January 2021

10.1016/S0162-0134(02)00438-5

Identifiers

DOI

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30 November 2017

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