Common solubilizers to estimate the Caco-2 transport of poorly water-soluble drugs (Q44149118)

30 November 2017

title

Common solubilizers to estimate the Caco-2 transport of poorly water-soluble drugs (English)

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30 November 2017

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Yutaka Takahashi

1

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30 November 2017

Hiromu Kondo

2

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30 November 2017

Tatsuo Yasuda

3

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30 November 2017

Takashi Watanabe

4

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30 November 2017

Shin-Ichiro Kobayashi

5

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30 November 2017

Shigeharu Yokohama

6

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30 November 2017

language of work or name

English

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publication date

1 October 2002

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International Journal of Pharmaceutics

30 November 2017

published in

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30 November 2017

volume

246

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30 November 2017

issue

1-2

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30 November 2017

page(s)

85-94

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Epithelial transport of drugs in cell culture. I: A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells

30 November 2017

cites work

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Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

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7 January 2021

Mechanisms and kinetics of uptake and efflux of L-methionine in an intestinal epithelial model (Caco-2)

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7 January 2021

In vitro permeability through caco-2 cells is not quantitatively predictive of in vivo absorption for peptide-like drugs absorbed via the dipeptide transporter system

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7 January 2021

Evaluation of Biocoat intestinal epithelium differentiation environment (3-day cultured Caco-2 cells) as an absorption screening model with improved productivity

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7 January 2021

Uptake of the cephalosporin, cephalexin, by a dipeptide transport carrier in the human intestinal cell line, Caco-2.

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7 January 2021

Transport of a large neutral amino acid (phenylalanine) in a human intestinal epithelial cell line: Caco-2.

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7 January 2021

Transport of bile acids in a human intestinal epithelial cell line, Caco-2.

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7 January 2021

Caco-2 cell monolayers as a model for drug transport across the intestinal mucosa

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7 January 2021

Permeability of lipophilic compounds in drug discovery using in-vitro human absorption model, Caco-2.

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7 January 2021

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

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7 January 2021

Effect of solubilizing excipients on permeation of poorly water-soluble compounds across Caco-2 cell monolayers

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7 January 2021

Evaluation of absorbability of poorly water-soluble drugs: validity of the use of additives

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7 January 2021

Analysis of drug permeation across Caco-2 monolayer: implication for predicting in vivo drug absorption.

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7 January 2021

Optimized conditions for prediction of intestinal drug permeability using Caco-2 cells

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7 January 2021

In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man--fact or myth

1 reference

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7 January 2021

10.1016/S0378-5173(02)00347-2

Identifiers

DOI

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30 November 2017

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