Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion. (Q44149480)

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2 December 2019

title

Inhibition of Kv2.1 voltage-dependent K+ channels in pancreatic beta-cells enhances glucose-dependent insulin secretion (English)

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2 December 2019

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9

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2 December 2019

Michael B. Wheeler

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2 December 2019

Patrick E. Macdonald

1

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2 December 2019

author name string

Sabine Sewing

2

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2 December 2019

Jianli Wang

3

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2 December 2019

Jamie W Joseph

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Simon R Smukler

5

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2 December 2019

George Sakellaropoulos

6

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2 December 2019

Jing Wang

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2 December 2019

Monique C Saleh

8

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2 December 2019

Robert G Tsushima

10

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2 December 2019

Anne Marie F Salapatek

11

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2 December 2019

language of work or name

English

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publication date

20 September 2002

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Journal of Biological Chemistry

2 December 2019

published in

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volume

277

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2 December 2019

issue

47

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2 December 2019

page(s)

44938-44945

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The role of ion channels in insulin secretion

2 December 2019

cites work

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ATP-sensitive K+ channels and insulin secretion: their role in health and disease.

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K+ channels: generating excitement in pancreatic beta-cells

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Metabolic coupling factors in pancreatic beta-cell signal transduction

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The pancreatic beta-cell as a fuel sensor: an electrophysiologist's viewpoint

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Starting insulin therapy in patients with type 2 diabetes: effectiveness, complications, and resource utilization.

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Calcium and delayed potassium currents in mouse pancreatic beta-cells under voltage-clamp conditions.

21 January 2018

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Beta-cell ion channels: keys to endodermal excitability

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The expression and regulation of depolarization-activated K+ channels in the insulin-secreting cell line INS-1.

21 January 2018

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9-Aminoacridine- and tetraethylammonium-induced reduction of the potassium permeability in pancreatic B-cells. Effects on insulin release and electrical properties

21 January 2018

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Tetraethylammonium potentiation of insulin release and inhibition of rubidium efflux in pancreatic islets

21 January 2018

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Members of the Kv1 and Kv2 voltage-dependent K(+) channel families regulate insulin secretion

21 January 2018

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Expression and function of pancreatic beta-cell delayed rectifier K+ channels. Role in stimulus-secretion coupling

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Internal block of human heart sodium channels by symmetrical tetra-alkylammoniums

21 January 2018

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Voltage-gated and resting membrane currents recorded from B-cells in intact mouse pancreatic islets.

21 January 2018

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Visualization of sequential exocytosis in rat pancreatic islet beta cells

21 January 2018

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Overexpression of uncoupling protein 2 inhibits glucose-stimulated insulin secretion from rat islets.

21 January 2018

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Enhanced glucose-dependent insulinotropic polypeptide secretion and insulinotropic action in glucagon-like peptide 1 receptor -/- mice.

21 January 2018

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Role of voltage- and Ca2(+)-dependent K+ channels in the control of glucose-induced electrical activity in pancreatic B-cells

21 January 2018

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Demonstration of A-currents in pancreatic islet cells.

21 January 2018

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Specificity of tetraethylammonium and quinine for three K channels in insulin-secreting cells

21 January 2018

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Synthesis, pharmacological characterization, and quantitative structure-activity relationship analyses of 3,7,9,9-tetraalkylbispidines: derivatives with specific bradycardic activity.

21 January 2018

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Tedisamil: master switch of nature?

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Mechanism of block by tedisamil of transient outward current in human ventricular subepicardial myocytes

21 January 2018

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Hanatoxin modifies the gating of a voltage-dependent K+ channel through multiple binding sites.

21 January 2018

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The role of plasma membrane K+ and Ca2+ permeabilities for glucose induction of slow Ca2+ oscillations in pancreatic beta-cells

21 January 2018

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Properties of the Ca-activated K+ channel in pancreatic β-cells

21 January 2018

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Characterization of a Ca2+-activated K+ current in insulin-secreting murine betaTC-3 cells

21 January 2018

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Potassium-selective ion channels in a transformed insulin-secreting cell line

21 January 2018

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Electrophysiology of the pancreatic beta-cell

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M205532200

1 reference

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2 December 2019

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