Ganglioside GD3 sensitizes human hepatoma cells to cancer therapy (Q44155998)

30 November 2017

Ganglioside GD3 sensitizes human hepatoma cells to cancer therapy (English)

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30 November 2017

hepatocellular carcinoma

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based on heuristic

inferred from title

author

José C Fernández-Checa

6

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30 November 2017

Albert Morales

2

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author name string

Raquel Paris

1

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30 November 2017

Olga Coll

3

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30 November 2017

Alberto Sánchez-Reyes

4

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30 November 2017

Carmen García-Ruiz

5

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30 November 2017

language of work or name

English

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publication date

25 September 2002

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Journal of Biological Chemistry

30 November 2017

7

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based on heuristic

inferred from page(s)

published in

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30 November 2017

277

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30 November 2017

49870-49876

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30 November 2017

51

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Apoptosis in cancer therapy: crossing the threshold

30 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.M208303200

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Enhancement of radiosensitivity by proteasome inhibition: implications for a role of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Ionizing radiation induces expression and binding activity of the nuclear factor kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Inhibition of TNF-induced apoptosis by NF-kappa B.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M208303200

NF-kappaB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Divergent role of ceramide generated by exogenous sphingomyelinases on NF-kappa B activation and apoptosis in human colon HT-29 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

The Rel/NF-kappaB family directly activates expression of the apoptosis inhibitor Bcl-x(L).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

E2F1 and c-Myc potentiate apoptosis through inhibition of NF-kappaB activity that facilitates MnSOD-mediated ROS elimination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Cell adhesion/recognition and signal transduction through glycosphingolipid microdomain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Requirement for GD3 ganglioside in CD95- and ceramide-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Commitment to apoptosis by GD3 ganglioside depends on opening of the mitochondrial permeability transition pore.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

GD3 glycosphingolipid contributes to Fas-mediated apoptosis via association with ezrin cytoskeletal protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Trafficking of ganglioside GD3 to mitochondria by tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Renal cell carcinoma-derived gangliosides suppress nuclear factor-kappaB activation in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Accumulation of glucosylceramides in multidrug-resistant cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Enhanced DNA binding and activation of transcription factors NF-kappa B and AP-1 by acetaldehyde in HEPG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Mitochondria and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

I kappa B interacts with the nuclear localization sequences of the subunits of NF-kappa B: a mechanism for cytoplasmic retention

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase by ionizing radiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Differential chemosensitizing effect of two glucosylceramide synthase inhibitors in hepatoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Mitochondria and cells produce reactive oxygen species in virtual anaerobiosis: relevance to ceramide-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Biochemistry of multidrug resistance mediated by the multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Altered sphingolipid metabolism in multidrug-resistant ovarian cancer cells is due to uncoupling of glycolipid biosynthesis in the Golgi apparatus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Oxidative damage of mitochondrial and nuclear DNA induced by ionizing radiation in human hepatoblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Multidrug resistance--a multiplex phenomenon

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

NF- kappa B and chemoresistance: potentiation of cancer drugs via inhibition of NF- kappa B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Daunorubicin activates NFkappaB and induces kappaB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

The role of sphingolipids in the process of signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Apoptogenic ganglioside GD3 directly induces the mitochondrial permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: implications for intracellular measurement of reactive nitrogen and oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

The glycosphingolipid composition of the human hepatoma cell line,Hep-G2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Apoptosis. Mitochondria--the death signal integrators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208303200

21 January 2018

Identifiers

DOI

10.1074/JBC.M208303200

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30 November 2017

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