New insights into the interactions between T-cell costimulatory blockade and conventional immunosuppressive drugs. (Q44200460)

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14 December 2019

title

New insights into the interactions between T-cell costimulatory blockade and conventional immunosuppressive drugs (English)

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14 December 2019

2

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14 December 2019

author name string

Masayuki Sho

1

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14 December 2019

Nader Najafian

3

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14 December 2019

Alan D Salama

4

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14 December 2019

Victor Dong

5

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14 December 2019

Akira Yamada

6

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14 December 2019

Koji Kishimoto

7

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14 December 2019

Hiroshi Harada

8

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14 December 2019

Isabela Schmitt

9

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14 December 2019

Mohamed H Sayegh

10

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14 December 2019

language of work or name

English

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publication date

1 November 2002

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14 December 2019

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14 December 2019

volume

236

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14 December 2019

page(s)

667-675

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issue

5

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Requirements for the promotion of allogeneic engraftment by anti-CD154 (anti-CD40L) monoclonal antibody under nonmyeloablative conditions

14 December 2019

cites work

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12 December 2020

Primarily vascularized allografts of hearts in mice. The role of H-2D, H-2K, and non-H-2 antigens in rejection

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12 December 2020

Experimental graft arteriosclerosis. I. The Lewis-to-F-344 allograft model

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12 December 2020

T-cell activation by the CD28 ligand B7 is required for cardiac allograft rejection in vivo

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12 December 2020

Long-term in vivo effects of rapamycin on humoral and cellular immune responses in the rat

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12 December 2020

Comparative effects of rapamycin, FK 506 and cyclosporine on antibody production, lymphocyte populations and immunoglobulin isotype switching in the rat

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12 December 2020

In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39.

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12 December 2020

Long-term acceptance of major histocompatibility complex mismatched cardiac allografts induced by CTLA4Ig plus donor-specific transfusion

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12 December 2020

Cyclosporin A inhibits CD40 ligand expression in T lymphocytes

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12 December 2020

Transplantation tolerance induced by CTLA4-Ig

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12 December 2020

CD28-B7 blockade after alloantigenic challenge in vivo inhibits Th1 cytokines but spares Th2.

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12 December 2020

CD40-gp39 interactions play a critical role during allograft rejection. Suppression of allograft rejection by blockade of the CD40-gp39 pathway

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12 December 2020

Chronic cardiac rejection in the LEW to F344 rat model. Blockade of CD28-B7 costimulation by CTLA4Ig modulates T cell and macrophage activation and attenuates arteriosclerosis

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12 December 2020

CTLA4-Ig plus bone marrow induces long-term allograft survival and donor specific unresponsiveness in the murine model. Evidence for hematopoietic chimerism

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12 December 2020

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

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12 December 2020

Immunopharmacology of rapamycin

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12 December 2020

CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris

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12 December 2020

Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates

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12 December 2020

Long-term survival and function of intrahepatic islet allografts in baboons treated with humanized anti-CD154

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12 December 2020

Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154.

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12 December 2020

CD40 ligand-dependent T cell activation: requirement of B7-CD28 signaling through CD40.

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12 December 2020

Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

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12 December 2020

Treatment of allograft recipients with donor-specific transfusion and anti-CD154 antibody leads to deletion of alloreactive CD8+ T cells and prolonged graft survival in a CTLA4-dependent manner

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12 December 2020

The role of costimulatory molecules as targets for new immunosuppressives in transplantation

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12 December 2020

The safety and efficacy of a two-dose daclizumab (zenapax) induction therapy in liver transplant recipients

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12 December 2020

Glucocorticoids in T cell development and function*.

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12 December 2020

The role of CD154-CD40 versus CD28-B7 costimulatory pathways in regulating allogeneic Th1 and Th2 responses in vivo

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12 December 2020

CD8+ T cells contribute to the development of transplant arteriosclerosis despite CD154 blockade

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12 December 2020

Differential effects of cyclosporine A, methylprednisolone, mycophenolate, and rapamycin on CD154 induction and requirement for NFkappaB: implications for tolerance induction

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12 December 2020

Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells

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12 December 2020

Host CD40 ligand deficiency induces long-term allograft survival and donor-specific tolerance in mouse cardiac transplantation but does not prevent graft arteriosclerosis

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12 December 2020

Intragraft interleukin-4 mRNA expression after short-term CD154 blockade may trigger delayed development of transplant arteriosclerosis in the absence of CD8+ T cells

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12 December 2020

Sirolimus (rapamycin) halts and reverses progression of allograft vascular disease in non-human primates

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12 December 2020

The role of newer monoclonal antibodies in renal transplantation

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12 December 2020

Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis.

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12 December 2020

Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases

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12 December 2020

Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection

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12 December 2020

CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

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12 December 2020

Distinct mechanisms for the induction and maintenance of allograft tolerance with CTLA4-Fc treatment

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12 December 2020

Use of CTLA4-Ig in combination with conventional immunosuppressive agents to prolong allograft survival

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12 December 2020

Chronic blockade of CD28-B7-mediated T-cell costimulation by CTLA4Ig reduces intimal thickening in MHC class I and II incompatible mouse heart allografts

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12 December 2020

Immunosuppressive effects of human CTLA4Ig in a non-human primate model of allogeneic pancreatic islet transplantation.

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12 December 2020

The role of T-cell costimulatory activation pathways in transplant rejection.

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12 December 2020

Impaired alloantigen-mediated T cell apoptosis and failure to induce long-term allograft survival in IL-2-deficient mice

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12 December 2020

Combined costimulation blockade plus rapamycin but not cyclosporine produces permanent engraftment

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12 December 2020

Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes

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12 December 2020

Inhibition of cell cycle progression by rapamycin induces T cell clonal anergy even in the presence of costimulation

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12 December 2020

Immunosuppressive strategies in transplantation

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12 December 2020

Finally, CTLA4Ig graduates to the clinic

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12 December 2020

10.1097/00000658-200211000-00018

Identifiers

DOI

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14 December 2019

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