The kinetic mechanism of phosphomevalonate kinase. (Q44211059)

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14 December 2019

title

The kinetic mechanism of phosphomevalonate kinase (English)

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14 December 2019

5

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14 December 2019

Stephen K Burley

6

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14 December 2019

4

Jeffrey B Bonanno

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14 December 2019

author name string

Daniel Pilloff

1

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14 December 2019

Kristina Dabovic

2

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14 December 2019

Michael J Romanowski

3

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14 December 2019

Thomas S Leyh

7

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language of work or name

English

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publication date

6 November 2002

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Journal of Biological Chemistry

14 December 2019

published in

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volume

278

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14 December 2019

issue

7

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page(s)

4510-4515

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Substrate-induced closure of the flap domain in the ternary complex structures provides insights into the mechanism of catalysis by 3-hydroxy-3-methylglutaryl-CoA reductase

14 December 2019

cites work

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The structure of a binary complex between a mammalian mevalonate kinase and ATP: insights into the reaction mechanism and human inherited disease

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Pig liver phosphomevalonate kinase. 1. Purification and properties

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Structural genomics of enzymes involved in sterol/isoprenoid biosynthesis

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New advances in lipid-modifying therapies for reducing cardiovascular risk

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Investigation of invariant serine/threonine residues in mevalonate kinase. Tests of the functional significance of a proposed substrate binding motif and a site implicated in human inherited disease

21 January 2018

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Biosynthesis of isoprenoids via mevalonate in Archaea: the lost pathway

21 January 2018

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Convergent evolution of similar enzymatic function on different protein folds: the hexokinase, ribokinase, and galactokinase families of sugar kinases

21 January 2018

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Cloning and characterization of ERG8, an essential gene of Saccharomyces cerevisiae that encodes phosphomevalonate kinase

21 January 2018

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Structural basis for the catalysis and substrate specificity of homoserine kinase

21 January 2018

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Structure of the Methanococcus jannaschii mevalonate kinase, a member of the GHMP kinase superfamily

21 January 2018

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Biochemical and X-ray crystallographic studies on shikimate kinase: The important structural role of the P-loop lysine

21 January 2018

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A kinetic analysis of coupled enzyme assays.

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GTPase activation of ATP sulfurylase: the mechanism.

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18 Use of competitive inhibitors to study substrate binding order

21 January 2018

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Bond order and charge localization in nucleoside phosphorothioates

21 January 2018

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The kinetics of enzyme-catalyzed reactions with two or more substrates or products

21 January 2018

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Purification and Characterization of Mevalonate Kinase from Suspension-Cultured Cells of Catharanthus roseus (L.) G. Don

21 January 2018

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The deoxyxylulose phosphate pathway of terpenoid biosynthesis in plants and microorganisms

21 January 2018

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Characterization of mevalonate kinase V377I, a mutant implicated in defective isoprenoid biosynthesis and HIDS/periodic fever syndrome.

21 January 2018

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Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily

21 January 2018

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Mapping the transition state for ATP hydrolysis: implications for enzymatic catalysis

21 January 2018

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Phosphomevalonate kinase from pig liver

21 January 2018

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Improved procedures for the synthesis of phosphomevalonate and for the assay and purification of pig liver phosphomevalonate kinase

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M210551200

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14 December 2019

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