Pre-treatment with R-lipoic acid alleviates the effects of GSH depletion in PC12 cells: implications for Parkinson's disease therapy (Q44214157)

30 November 2017

Pre-treatment with R-lipoic acid alleviates the effects of GSH depletion in PC12 cells: implications for Parkinson's disease therapy (English)

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30 November 2017

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30 November 2017

5

Ames BN

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30 November 2017

Bharat S

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30 November 2017

Cochran BC

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2

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30 November 2017

Liu J

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30 November 2017

Andersen JK

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30 November 2017

1 October 2002

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30 November 2017

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30 November 2017

23

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30 November 2017

479-486

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30 November 2017

4-5

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Parkinson's disease--redox mechanisms

30 November 2017

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Effect of buthionine sulfoximine, a synthesis inhibitor of the antioxidant glutathione, on the murine nigrostriatal neurons

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Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson's disease

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(R)-alpha-lipoic acid reverses the age-associated increase in susceptibility of hepatocytes to tert-butylhydroperoxide both in vitro and in vivo

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Lipoic acid increases de novo synthesis of cellular glutathione by improving cystine utilization

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Effects of arachidonic acid on respiratory activities in isolated brain mitochondria

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7 January 2021

Glutathione depletion in PC12 results in selective inhibition of mitochondrial complex I activity. Implications for Parkinson's disease.

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S-glutathiolated hepatocyte proteins and insulin disulfides as substrates for reduction by glutaredoxin, thioredoxin, protein disulfide isomerase, and glutathione.

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Mitochondrial complex I defects in aging.

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Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes--reversal with (R)-alpha-lipoic acid supplementation.

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Stereospecific effects of R-lipoic acid on buthionine sulfoximine-induced cataract formation in newborn rats

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Lipoamide dehydrogenase deficiency with primary lactic acidosis: favorable response to treatment with oral lipoic acid

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Glutathione depletion in tissues after administration of buthionine sulphoximine

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alpha-Lipoic acid as a biological antioxidant

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Neuroprotection by the metabolic antioxidant alpha-lipoic acid

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7 January 2021

Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease

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Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients.

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Glutathione depletion and formation of glutathione-protein mixed disulfide following exposure of brain mitochondria to oxidative stress.

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Chemistry and biochemistry of oxidative stress in neurodegenerative disease

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Lipoic and dihydrolipoic acids as antioxidants. A critical evaluation.

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Glutathione biosynthesis; gamma-glutamylcysteine synthetase from rat kidney

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A positively charged alpha-lipoic acid analogue with increased cellular uptake and more potent immunomodulatory activity

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Determination of oxidized and reduced lipoic acid using high-performance liquid chromatography and coulometric detection

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Thiol oxidation and loss of mitochondrial complex I precede excitatory amino acid-mediated neurodegeneration.

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Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid

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Thioctic Acid and Dihydrolipoic Acid are Novel Antioxidants Which Interact With Reactive Oxygen Species

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7 January 2021

Buthionine sulfoximine-induced glutathione depletion. Its effect on antioxidants, lipid peroxidation and calcium homeostasis in the lung

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7 January 2021

Neuroprotective effects of alpha-lipoic acid and its positively charged amide analogue

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Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines

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Neuroprotective effects of alpha-lipoic acid and its enantiomers demonstrated in rodent models of focal cerebral ischemia.

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7 January 2021

Glutathione depletion potentiates MPTP and MPP+ toxicity in nigral dopaminergic neurones.

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The antioxidant effect of DL-alpha-lipoic acid on copper-induced acute hepatitis in Long-Evans Cinnamon (LEC) rats

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Effect of lipoic acid in a patient with defective activity of pyruvate dehydrogenase, 2-oxoglutarate dehydrogenase, and branched-chain keto acid dehydrogenase

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Alpha-lipoic acid in the treatment of diabetic peripheral and cardiac autonomic neuropathy

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7 January 2021

10.1016/S0161-813X(02)00035-9

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DOI

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30 November 2017

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