Effects of immunosuppressants, calcineurin inhibition, and blockade of endoplasmic reticulum calcium channels on free fatty acid efflux from the ischemic/reperfused rat cerebral cortex (Q44223718)

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scientific article published in December 2002

Language	Label	Description	Also known as
English	Effects of immunosuppressants, calcineurin inhibition, and blockade of endoplasmic reticulum calcium channels on free fatty acid efflux from the ischemic/reperfused rat cerebral cortex	scientific article published in December 2002

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scholarly article

1 reference

Europe PubMed Central

1 December 2017

Effects of immunosuppressants, calcineurin inhibition, and blockade of endoplasmic reticulum calcium channels on free fatty acid efflux from the ischemic/reperfused rat cerebral cortex (English)

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Europe PubMed Central

1 December 2017

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endoplasmic reticulum

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immunosuppression

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based on heuristic

inferred from title

author name string

Phillis JW

1

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Europe PubMed Central

1 December 2017

Diaz FG

2

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Europe PubMed Central

1 December 2017

O'Regan MH

3

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Europe PubMed Central

1 December 2017

Pilitsis JG

4

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Europe PubMed Central

1 December 2017

language of work or name

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publication date

1 December 2002

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Europe PubMed Central

1 December 2017

number of pages

13

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based on heuristic

inferred from page(s)

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Europe PubMed Central

1 December 2017

957

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Europe PubMed Central

1 December 2017

12-24

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Europe PubMed Central

1 December 2017

1

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Europe PubMed Central

1 December 2017

In vivo prevention of adriamycin cardiotoxicity by cyclosporin A or FK506

1 reference

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Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function

1 reference

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Calcineurin and mitochondrial function in glutamate-induced neuronal cell death.

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s-cyclophilin is retained intracellularly via a unique COOH-terminal sequence and colocalizes with the calcium storage protein calreticulin

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Mitochondria recycle Ca(2+) to the endoplasmic reticulum and prevent the depletion of neighboring endoplasmic reticulum regions

1 reference

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7 January 2021

Reversible inhibition of calcineurin by the polyphenolic aldehyde gossypol.

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The permeability transition pore. Control points of a cyclosporin A-sensitive mitochondrial channel involved in cell death

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7 January 2021

Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2.

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7 January 2021

Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein

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7 January 2021

Cyclosporin A-sensitive and insensitive mechanisms produce the permeability transition in mitochondria

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7 January 2021

Neuroprotective actions of FK506 in experimental stroke: in vivo evidence against an antiexcitotoxic mechanism.

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7 January 2021

Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux

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7 January 2021

Immunophilin FK506 binding protein associated with inositol 1,4,5-trisphosphate receptor modulates calcium flux

1 reference

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7 January 2021

Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channel

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7 January 2021

Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity

1 reference

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7 January 2021

The immunosuppressant FK506 ameliorates ischaemic damage in the rat brain.

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7 January 2021

Ryanodine sensitizes the cardiac Ca(2+) release channel (ryanodine receptor isoform 2) to Ca(2+) activation and dissociates as the channel is closed by Ca(2+) depletion

1 reference

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7 January 2021

The phospholipase A2 inhibitor, quinacrine, reduces infarct size in rats after transient middle cerebral artery occlusion.

1 reference

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7 January 2021

Intracellular calcium signals regulating cytosolic phospholipase A2 translocation to internal membranes

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7 January 2021

Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases

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7 January 2021

Dantrolene Prevents Glutamate Cytotoxicity and Ca2+Release from Intracellular Stores in Cultured Cerebral Cortical Neurons

1 reference

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7 January 2021

Cyclosporin A, but not FK 506, protects mitochondria and neurons against hypoglycemic damage and implicates the mitochondrial permeability transition in cell death.

1 reference

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7 January 2021

Immunophilins in protein folding and immunosuppression.

1 reference

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7 January 2021

Xestospongins: potent membrane permeable blockers of the inositol 1,4,5-trisphosphate receptor

1 reference

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7 January 2021

Release and sequestration of calcium by ryanodine-sensitive stores in rat hippocampal neurones

1 reference

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7 January 2021

The effects of dantrolene alone or in combination with nimodipine in glutamate-induced neurotoxicity in cerebellar granular cell cultures of rat pups

1 reference

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7 January 2021

Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin

1 reference

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7 January 2021

Immunophilins: beyond immunosuppression

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7 January 2021

Trifluoperazine and dibucaine-induced inhibition of glutamate-induced mitochondrial depolarization in rat cultured forebrain neurones

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7 January 2021

An immunosuppressant, FK506, protects hippocampal neurons from forebrain ischemia in the mongolian gerbil.

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7 January 2021

ATP stimulates calcium-dependent glutamate release from cultured astrocytes

1 reference

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7 January 2021

The immunosuppressants cyclosporin A and FK506 equally ameliorate brain damage due to 30-min middle cerebral artery occlusion in hyperglycemic rats.

1 reference

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7 January 2021

The calmodulin antagonist trifluoperazine in transient focal brain ischemia in rats. Anti-ischemic effect and therapeutic window

1 reference

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7 January 2021

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

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7 January 2021

Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion.

1 reference

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7 January 2021

Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis

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7 January 2021

Chromaffin-cell stimulation triggers fast millimolar mitochondrial Ca2+ transients that modulate secretion

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7 January 2021

Potential role of calcineurin for brain ischemia and traumatic injury

1 reference

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7 January 2021

Mitochondria and neuronal survival

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7 January 2021

Ca2+ marks: miniature calcium signals in single mitochondria driven by ryanodine receptors

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Disturbances of the functioning of endoplasmic reticulum: a key mechanism underlying neuronal cell injury?

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Cerebroprotective action of the phospholipase inhibitor quinacrine in the ischemia/reperfused gerbil hippocampus

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7 January 2021

Mechanisms of glutamate and aspartate release in the ischemic rat cerebral cortex.

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Inhibition of mitochondrial Na(+)/Ca(2+) exchange by 7-chloro-5-(2-chlorophenyl)-1,5-dihydro-4,1-benzothiazepin-2(3H)-one attenuates free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury

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7 January 2021

Differential effects of phospholipase inhibitors on free fatty acid efflux in rat cerebral cortex during ischemia-reperfusion injury

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7 January 2021

Structural proximity of mitochondria to calcium release units in rat ventricular myocardium may suggest a role in Ca2+ sequestration

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Identification of simian cyclophilin A as a calreticulin-binding protein in yeast two-hybrid screen and demonstration of cyclophilin A interaction with calreticulin

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7 January 2021

Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses

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7 January 2021

Characterization of phospholipase A2 (PLA2) activity in gerbil brain: enhanced activities of cytosolic, mitochondrial, and microsomal forms after ischemia and reperfusion.

1 reference

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7 January 2021

Activation of cPLA2, PKC, and ERKs in the rat cerebral cortex during ischemia/reperfusion.

1 reference

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7 January 2021

Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

1 reference

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7 January 2021

Cyclosporin A inhibits inositol 1,4,5-trisphosphate-dependent Ca2+ signals by enhancing Ca2+ uptake into the endoplasmic reticulum and mitochondria

1 reference

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7 January 2021

Immunophilins in the nervous system

1 reference

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7 January 2021

Calmodulin in ischemic neurotoxicity of rat hippocampus in vitro

1 reference

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7 January 2021

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase

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7 January 2021

Neuroprotective effect of FK506, an immunosuppressant, on transient global ischemia in gerbil.

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7 January 2021

Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat.

1 reference

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7 January 2021

Amelioration by cyclosporin A of brain damage in transient forebrain ischemia in the rat.

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7 January 2021

Calreticulin modulates capacitative Ca2+ influx by controlling the extent of inositol 1,4,5-trisphosphate-induced Ca2+ store depletion.

1 reference

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7 January 2021

Effect of immunosuppressant FK506 on ischemia-induced degeneration of hippocampal neurons in gerbils

1 reference

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7 January 2021

Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia.

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7 January 2021

Cytosolic Ca2+ changes during in vitro ischemia in rat hippocampal slices: major roles for glutamate and Na+-dependent Ca2+ release from mitochondria.

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Phenothiazines reduce ischemic damage to the central nervous system

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7 January 2021

Identifiers

10.1016/S0006-8993(02)03578-3

1 reference

Europe PubMed Central

1 December 2017

1 reference

Europe PubMed Central

1 December 2017

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