Simple and sensitive determination of the new antitumor drug CKD-602 in human plasma by liquid chromatography. (Q44263865)

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16 December 2019

title

Simple and sensitive determination of the new antitumor drug CKD-602 in human plasma by liquid chromatography (English)

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16 December 2019

4

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16 December 2019

1

Joo Youn Cho

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16 December 2019

author name string

Hyo Bum Seo

2

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16 December 2019

Kyung Sang Yu

3

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16 December 2019

So Young Yi

5

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16 December 2019

In Jin Jang

6

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16 December 2019

Sang Goo Shin

7

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16 December 2019

publication date

1 January 2003

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Journal of Chromatography B Analytical Technologies in the Biomedical and Life Sciences

16 December 2019

published in

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16 December 2019

volume

784

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16 December 2019

issue

1

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16 December 2019

page(s)

25-31

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The current status of camptothecin analogues as antitumor agents

16 December 2019

cites work

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Topoisomerase I inhibitors: topotecan and irenotecan

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Antitumor activity of 7-[2-(N-isopropylamino)ethyl]-(20S)-camptothecin, CKD602, as a potent DNA topoisomerase I inhibitor

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Preclinical and phase I clinical studies with Ckd-602, a novel camptothecin derivative

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7 January 2021

A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues

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Analysis of the active lactone form of 9-aminocamptothecin in plasma using solid-phase extraction and high-performance liquid chromatography

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7 January 2021

The structural basis of camptothecin interactions with human serum albumin: impact on drug stability

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7 January 2021

On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex

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7 January 2021

Phase I and pharmacokinetics study of topotecan, a new topoisomerase I inhibitor

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Pharmacokinetics and pharmacodynamics of topotecan administered daily for 5 days every 3 weeks

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Reversed-phase high-performance liquid chromatographic method for the simultaneous quantitation of the carboxylate and lactone forms of the camptothecin derivative irinotecan, CPT-11, and its metabolite SN-38 in plasma

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7 January 2021

High-performance liquid chromatographic determination of irinotecan (CPT-11) and its active metabolite (SN-38) in human plasma

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7 January 2021

High-performance liquid chromatographic determination of the novel antitumour drug topotecan and topotecan as the total of the lactone plus carboxylate forms, in human plasma.

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7 January 2021

10.1016/S1570-0232(02)00750-X

Identifiers

DOI

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16 December 2019

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