Dysfunction of mitochondrial respiratory chain complex I in human failing myocardium is not due to disturbed mitochondrial gene expression (Q44264771)

1 December 2017

Dysfunction of mitochondrial respiratory chain complex I in human failing myocardium is not due to disturbed mitochondrial gene expression (English)

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1 December 2017

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Robert J Scheubel

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1 December 2017

Mike Tostlebe

2

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1 December 2017

Andreas Simm

3

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1 December 2017

Susanne Rohrbach

4

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1 December 2017

Roland Prondzinsky

5

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1 December 2017

Frank N Gellerich

6

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1 December 2017

Rolf Edgar Silber

7

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1 December 2017

Juergen Holtz

8

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1 December 2017

language of work or name

English

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publication date

1 December 2002

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Journal of the American College of Cardiology

1 December 2017

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1 December 2017

40

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1 December 2017

12

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1 December 2017

2174-2181

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Cardiac involvement in primary myopathies

1 December 2017

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Mitochondrial DNA mutations and mitochondrial abnormalities in dilated cardiomyopathy

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Mitochondrial dysfunction in congenital nephrotic syndrome

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Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction

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Age-dependent myocardial reinduction of apoptosis inhibitors under VAD in heart failure

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Apoptotic pathway activation from mitochondria and death receptors without caspase-3 cleavage in failing human myocardium: fragile balance of myocyte survival?

1 reference

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Major changes in complex I activity in mitochondria from aged rats may not be detected by direct assay of NADH:coenzyme Q reductase

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Different sensitivity of rabbit heart and skeletal muscle to endotoxin-induced impairment of mitochondrial function

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Tumor necrosis factor-alpha and tumor necrosis factor receptors in the failing human heart

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Low levels of mitochondrial transcription factor A in mitochondrial DNA depletion

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The interleukin-6/interleukin-6-receptor system is activated in donor hearts.

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Does nitric oxide modulate mitochondrial energy generation and apoptosis?

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Persistent inhibition of cell respiration by nitric oxide: crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione.

1 reference

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Expression, activity and functional significance of inducible nitric oxide synthase in the failing human heart

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Role of nitric oxide in the control of mitochondrial function.

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Oxidative stress and apoptosis in heart failure progression

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Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart

1 reference

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Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium

1 reference

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Titrating the effects of mitochondrial complex I impairment in the cell physiology

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Abnormal mitochondrial respiration in failed human myocardium

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Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in the conscious dog.

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Novel molecular mechanism of increased myocardial endothelin-1 expression in the failing heart involving the transcriptional factor hypoxia-inducible factor-1alpha induced for impaired myocardial energy metabolism

1 reference

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Deloading of the left ventricle by ventricular assist device normalizes increased expression of endothelin ET(A) receptors but not endothelin-converting enzyme-1 in patients with end-stage heart failure

1 reference

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Endothelin-1 production is enhanced by rotenone, a mitochondrial complex I inhibitor, in cultured rat cardiomyocytes

1 reference

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7 January 2021

High-energy phosphate metabolism and creatine kinase in failing hearts: a new porcine model

1 reference

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7 January 2021

Downregulation of the Na(+)-creatine cotransporter in failing human myocardium and in experimental heart failure.

1 reference

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Adenylate kinase-catalyzed phosphotransfer in the myocardium : increased contribution in heart failure

1 reference

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7 January 2021

Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase

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Excessive formation of hydroxyl radicals and aldehydic lipid peroxidation products in cultured skin fibroblasts from patients with complex I deficiency

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Mitochondrial function in heart muscle from patients with idiopathic dilated cardiomyopathy

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Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines

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Abnormal cardiac and skeletal muscle mitochondrial function in pacing-induced cardiac failure

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Identifiers

DOI

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1 December 2017

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