Regulatory T cell frequency and modulation of IFN-gamma and IL-17 in active and latent tuberculosis (Q44266163)

1 December 2017

Regulatory T cell frequency and modulation of IFN-gamma and IL-17 in active and latent tuberculosis (English)

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1 December 2017

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Nancy D Marin

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1 December 2017

Sara C París

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1 December 2017

Viviana M Vélez

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1 December 2017

Carlos A Rojas

4

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1 December 2017

Mauricio Rojas

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1 December 2017

Luis F García

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1 December 2017

1 July 2010

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1 December 2017

90

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1 December 2017

252-261

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4

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Control of human host immunity to mycobacteria.

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IFNgamma response to Mycobacterium tuberculosis, risk of infection and disease in household contacts of tuberculosis patients in Colombia

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CD4(+) T cells are required for the development of cytotoxic CD8(+) T cells during Mycobacterium tuberculosis infection

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Multifunctional, high-level cytokine-producing Th1 cells in the lung, but not spleen, correlate with protection against Mycobacterium tuberculosis aerosol challenge in mice

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Distinct, specific IL-17- and IL-22-producing CD4+ T cell subsets contribute to the human anti-mycobacterial immune response

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Alphabeta T cell receptor-positive cells and interferon-gamma, but not inducible nitric oxide synthase, are critical for granuloma necrosis in a mouse model of mycobacteria-induced pulmonary immunopathology

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IL-23 and IL-17 in tuberculosis

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IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge

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Cutting edge: Human Th17 cells are identified as bearing CCR2+CCR5- phenotype.

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Cutting edge: IFN-gamma regulates the induction and expansion of IL-17-producing CD4 T cells during mycobacterial infection

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Cross-modulation by transforming growth factor beta in human tuberculosis: suppression of antigen-driven blastogenesis and interferon gamma production

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Dynamic changes in pro- and anti-inflammatory cytokine profiles and gamma interferon receptor signaling integrity correlate with tuberculosis disease activity and response to curative treatment

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A role for CD4+CD25+ T cells in regulation of the immune response during human tuberculosis

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Regulatory T cells are expanded in blood and disease sites in patients with tuberculosis

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In vitro expansion of CD4+CD25highFOXP3+CD127low/- regulatory T cells from peripheral blood lymphocytes of healthy Mycobacterium tuberculosis-infected humans

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Regulatory T cells depress immune responses to protective antigens in active tuberculosis

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Expansion and function of Foxp3-expressing T regulatory cells during tuberculosis

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Cutting Edge: Regulatory T cells prevent efficient clearance of Mycobacterium tuberculosis

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CD4(+)CD25(+)FoxP3(+) regulatory T cells suppress Mycobacterium tuberculosis immunity in patients with active disease

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Immunosuppression during active tuberculosis is characterized by decreased interferon- gamma production and CD25 expression with elevated forkhead box P3, transforming growth factor- beta , and interleukin-4 mRNA levels

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Increased frequency of CD4(+)CD25(high) Treg cells inhibit BCG-specific induction of IFN-gamma by CD4(+) T cells from TB patients.

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Mannose-capped lipoarabinomannan- and prostaglandin E2-dependent expansion of regulatory T cells in human Mycobacterium tuberculosis infection

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Regulatory T cells modulate Th17 responses in patients with positive tuberculin skin test results

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Natural versus adaptive regulatory T cells

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Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+ CD25+ T cells

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CD4+CD25highFOXP3+ regulatory T cells in peripheral blood are primarily of effector memory phenotype.

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Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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Depressed T‐Cell Interferon‐γ Responses in Pulmonary Tuberculosis: Analysis of Underlying Mechanisms and Modulation with Therapy

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CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.

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How regulatory T cells work

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Mechanisms of foxp3+ T regulatory cell-mediated suppression

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In vitro synthesis of interferon-gamma, interleukin-4, transforming growth factor-beta and interleukin-1 beta by peripheral blood mononuclear cells from tuberculosis patients: relationship with the severity of pulmonary involvement.

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Regulatory T cells and infection: a dangerous necessity

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Suppressor T cells--they're back and critical for regulation of autoimmunity!

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Absence of regulatory T-cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft-versus-host disease

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CD4+ CD25+ transforming growth factor-beta-producing T cells are present in the lung in murine tuberculosis and may regulate the host inflammatory response

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Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells

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Interleukin-2 enhances CD4+ T cell memory by promoting the generation of IL-7R alpha-expressing cells

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Evaluation of standard chemotherapy in the guinea pig model of tuberculosis

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Tuberculosis is associated with a down-modulatory lung immune response that impairs Th1-type immunity

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Interaction of Mycobacterium tuberculosis-induced transforming growth factor beta1 and interleukin-10.

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.TUBE.2010.05.003

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1 December 2017

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