Backbone dynamics of the cytotoxic ribonuclease alpha-sarcin by 15N NMR relaxation methods. (Q44274713)

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16 December 2019

title

Backbone dynamics of the cytotoxic ribonuclease alpha-sarcin by 15N NMR relaxation methods (English)

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16 December 2019

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Alvaro Martínez-del-Pozo

5

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16 December 2019

José G Gavilanes

6

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16 December 2019

Marta Bruix

8

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Jose Manuel Pérez-Cañadillas

16 December 2019

1

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16 December 2019

Ramón Campos-Olivas

3

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16 December 2019

author name string

Marc Guenneugues

2

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16 December 2019

Jorge Santoro

4

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16 December 2019

Manuel Rico

7

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16 December 2019

publication date

1 December 2002

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Journal of Biomolecular NMR

16 December 2019

published in

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16 December 2019

volume

24

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16 December 2019

issue

4

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16 December 2019

page(s)

301-316

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Internal mobility in the partially folded DNA binding and dimerization domains of GAL4: NMR analysis of the N-H spectral density functions

16 December 2019

cites work

1 reference

12 December 2020

Role of histidine-50, glutamic acid-96, and histidine-137 in the ribonucleolytic mechanism of the ribotoxin alpha-sarcin

1 reference

12 December 2020

The role of backbone motions in ligand binding to the c-Src SH3 domain

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12 December 2020

Deletion of the NH2-terminal beta-hairpin of the ribotoxin alpha-sarcin produces a nontoxic but active ribonuclease.

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12 December 2020

Spectral density function mapping using 15N relaxation data exclusively

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12 December 2020

Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation

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12 December 2020

Backbone dynamics of ribonuclease T1 and its complex with 2'GMP studied by two-dimensional heteronuclear NMR spectroscopy

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12 December 2020

Overproduction and purification of biologically active native fungal alpha-sarcin in Escherichia coli.

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12 December 2020

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

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12 December 2020

Crystal structures of restrictocin-inhibitor complexes with implications for RNA recognition and base flipping

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12 December 2020

Backbone dynamics and solution structure refinement of the 15N-labeled human oncogenic protein p13MTCP1: comparison with X-ray data

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12 December 2020

Interpretation of 15N NMR relaxation data of globular proteins using hydrodynamic calculations with HYDRONMR.

1 reference

12 December 2020

Characterization of pKa values and titration shifts in the cytotoxic ribonuclease alpha-sarcin by NMR. Relationship between electrostatic interactions, structure, and catalytic function.

1 reference

12 December 2020

Protein dynamics studied by rotating frame 15N spin relaxation times.

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12 December 2020

MOLMOL: a program for display and analysis of macromolecular structures

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12 December 2020

An empirical relationship between rotational correlation time and solvent accessible surface area

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12 December 2020

ALPHA SARCIN, A NEW ANTITUMOR AGENT. I. ISOLATION, PURIFICATION, CHEMICAL COMPOSITION, AND THE IDENTITY OF A NEW AMINO ACID.

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12 December 2020

Kinetic study of the cytotoxic effect of alpha-sarcin, a ribosome inactivating protein from Aspergillus giganteus, on tumour cell lines: protein biosynthesis inhibition and cell binding

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12 December 2020

Rotational diffusion anisotropy of proteins from simultaneous analysis of 15N and 13C alpha nuclear spin relaxation

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12 December 2020

Protein backbone dynamics revealed by quasi spectral density function analysis of amide N-15 nuclei

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12 December 2020

Hydrodynamic properties of rigid particles: comparison of different modeling and computational procedures

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12 December 2020

Millisecond-timescale motions contribute to the function of the bacterial response regulator protein Spo0F

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12 December 2020

Involvement of the amino-terminal beta-hairpin of the Aspergillus ribotoxins on the interaction with membranes and nonspecific ribonuclease activity.

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12 December 2020

Structural plasticity in a remodeled protein-protein interface

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12 December 2020

Insights into specificity of cleavage and mechanism of cell entry from the crystal structure of the highly specific Aspergillus ribotoxin, restrictocin

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12 December 2020

Frequency spectrum of NH bonds in eglin c from spectral density mapping at multiple fields

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12 December 2020

Mapping of the spectral densities of N-H bond motions in eglin c using heteronuclear relaxation experiments

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12 December 2020

Off-resonance rf fields in heteronuclear NMR: Application to the study of slow motions

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12 December 2020

Unusual lack of internal mobility and fast overall tumbling in oxidized flavodoxin from Anacystis nidulans

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12 December 2020

A hot spot of binding energy in a hormone-receptor interface

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12 December 2020

Molecular dissection of mitogillin reveals that the fungal ribotoxins are a family of natural genetically engineered ribonucleases

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12 December 2020

An Off-resonance Rotating Frame Relaxation Experiment for the Investigation of Macromolecular Dynamics Using Adiabatic Rotations

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12 December 2020

Microsecond time scale dynamics in the RXR DNA-binding domain from a combination of spin-echo and off-resonance rotating frame relaxation measurements

1 reference

12 December 2020

Backbone dynamics of Escherichia coli ribonuclease HI: correlations with structure and function in an active enzyme

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12 December 2020

Changes in side-chain and backbone dynamics identify determinants of specificity in RNA recognition by human U1A protein

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12 December 2020

Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy

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12 December 2020

HYDRONMR: prediction of NMR relaxation of globular proteins from atomic-level structures and hydrodynamic calculations

1 reference

12 December 2020

Protein hydration observed by X-ray diffraction. Solvation properties of penicillopepsin and neuraminidase crystal structures.

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12 December 2020

Cytotoxic mechanism of the ribotoxin alpha-sarcin. Induction of cell death via apoptosis

1 reference

12 December 2020

The highly refined solution structure of the cytotoxic ribonuclease alpha-sarcin reveals the structural requirements for substrate recognition and ribonucleolytic activity

1 reference

12 December 2020

Probing the Backbone Dynamics of Oxidized and Reduced Rat Microsomal Cytochromeb5via15N Rotating Frame NMR Relaxation Measurements: Biological Implications†

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1021698308683

1 reference

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Dimensions Publication ID

16 December 2019

1033160320

0 references

1 reference

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