An inhibitory function for JNK in the regulation of IGF-I signaling in breast cancer (Q44294950)

1 December 2017

An inhibitory function for JNK in the regulation of IGF-I signaling in breast cancer (English)

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1 December 2017

Cindy L Mamay

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1 December 2017

Amy M Mingo-Sion

2

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1 December 2017

Doug M Wolf

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1 December 2017

Marion D Molina

4

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1 December 2017

Carla L Van Den Berg

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1 December 2017

language of work or name

English

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publication date

1 January 2003

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1 December 2017

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1 December 2017

22

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1 December 2017

4

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1 December 2017

602-614

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206186

1 December 2017

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cites work

Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

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The JUN kinase/stress-activated protein kinase pathway is required for epidermal growth factor stimulation of growth of human A549 lung carcinoma cells.

21 January 2018

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Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase

21 January 2018

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Transactivation of ErbB2 and ErbB3 by tumor necrosis factor-alpha and anisomycin leads to impaired insulin signaling through serine/threonine phosphorylation of IRS proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

Insulin-like growth factor 1 receptors (IGF1-R) and IGF1 in human breast tumors

21 January 2018

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The Jun kinase/stress-activated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

The role of MAP kinase in TPA-mediated cell cycle arrest of human breast cancer cells

21 January 2018

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7 January 2021

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Regulation of cell death protease caspase-9 by phosphorylation

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38)

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Insulin differentially regulates SAPKs/JNKs and ERKs in CHO cells overexpressing human insulin receptors

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Stress-activated kinases regulate protein stability

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Insulin-like growth factor (IGF)-I rescues breast cancer cells from chemotherapy-induced cell death--proliferative and anti-apoptotic effects

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Selective interaction of JNK protein kinase isoforms with transcription factors

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

The stress-activated protein kinase subfamily of c-Jun kinases

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Insulin-like growth factor I-induced degradation of insulin receptor substrate 1 is mediated by the 26S proteasome and blocked by phosphatidylinositol 3'-kinase inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Phosphatidylinositol 3-kinase mediates epidermal growth factor-induced activation of the c-Jun N-terminal kinase signaling pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Requirement of phosphatidylinositol-3 kinase for activation of JNK/SAPKs by PDGF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Activation of cJun NH2-terminal kinase/stress-activated protein kinase by insulin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Insulin-like growth factor I activates c-Jun N-terminal kinase in MCF-7 breast cancer cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Insulin-like growth factor-I inhibits the stress-activated protein kinase/c-Jun N-terminal kinase.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Signal transduction by tumor necrosis factor mediated by JNK protein kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Polyethylene glycol conjugated insulin-like growth factor binding protein-1 (IGFBP-1) inhibits growth of breast cancer in athymic mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Integration of MAP kinase signal transduction pathways at the serum response element

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206186

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206186

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1 December 2017

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