Determinants of the in vivo folding of the prion protein. A bipartite function of helix 1 in folding and aggregation (Q44295681)

1 December 2017

title

Determinants of the in vivo folding of the prion protein. A bipartite function of helix 1 in folding and aggregation (English)

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1 December 2017

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1

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7

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1 December 2017

Johanna Heske

2

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1 December 2017

Ulrich Heller

3

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1 December 2017

Anja Reintjes

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1 December 2017

Walter Muranyi

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1 December 2017

Ismail Moarefi

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language of work or name

English

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publication date

29 January 2003

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Journal of Biological Chemistry

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number of pages

10

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based on heuristic

inferred from page(s)

published in

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volume

278

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1 December 2017

issue

17

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1 December 2017

page(s)

14961-14970

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Site-specific characterization of the N-linked glycans of murine prion protein by high-performance liquid chromatography/electrospray mass spectrometry and exoglycosidase digestions

1 December 2017

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Asparagine-linked glycosylation of the scrapie and cellular prion proteins

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Scrapie prion protein contains a phosphatidylinositol glycolipid

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Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible

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NMR structure of the mouse prion protein domain PrP(121-231)

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NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231).

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Prion protein devoid of the octapeptide repeat region restores susceptibility to scrapie in PrP knockout mice.

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Molecular dynamics simulation of human prion protein including both N-linked oligosaccharides and the GPI anchor.

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PrPc glycoform heterogeneity as a function of brain region: implications for selective targeting of neurons by prion strains

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Acquisition of protease resistance by prion proteins in scrapie-infected cells does not require asparagine-linked glycosylation

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Molecular basis of phenotypic variability in sporadic Creutzfeldt-Jakob disease

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Molecular analysis of bovine spongiform encephalopathy and scrapie strain variation

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Expression of unglycosylated mutated prion protein facilitates PrP(Sc) formation in neuroblastoma cells infected with different prion strains

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Glycosylation influences cross-species formation of protease-resistant prion protein

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Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease

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Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

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Geldanamycin restores a defective heat shock response in vivo

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Recombinant full-length murine prion protein, mPrP(23-231): purification and spectroscopic characterization.

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Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein

21 January 2018

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Membrane topology influences N-glycosylation of the prion protein

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Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells

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Cell-free formation of protease-resistant prion protein.

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Prion protein expression in Chinese hamster ovary cells using a glutamine synthetase selection and amplification system

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A nascent secretory protein may traverse the ribosome/endoplasmic reticulum translocase complex as an extended chain

21 January 2018

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COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform

21 January 2018

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Protein glucosylation and its role in protein folding

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Intracellular functions of N-linked glycans

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Cell-surface anchoring of proteins via glycosyl-phosphatidylinositol structures

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The structure and biosynthesis of glycosyl phosphatidylinositol protein anchors

21 January 2018

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Determinants for glycophospholipid anchoring of the Saccharomyces cerevisiae GAS1 protein to the plasma membrane

21 January 2018

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Biosynthesis of glycosylphosphatidylinositol (GPI)-anchored membrane proteins in intact cells: specific amino acid requirements adjacent to the site of cleavage and GPI attachment

21 January 2018

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Site-specific mutations in the COOH-terminus of placental alkaline phosphatase: a single amino acid change converts a phosphatidylinositol-glycan-anchored protein to a secreted protein

21 January 2018

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Binding of prion protein to lipid membranes and implications for prion conversion

21 January 2018

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Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85

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The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme

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Protein oligomerization in the endoplasmic reticulum

21 January 2018

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Protein degradation in the endoplasmic reticulum

21 January 2018

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Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation

21 January 2018

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Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein

21 January 2018

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The 37-kDa/67-kDa laminin receptor acts as the cell-surface receptor for the cellular prion protein

21 January 2018

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Complementary hydropathy identifies a cellular prion protein receptor

21 January 2018

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Signal transduction through prion protein

21 January 2018

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The human 37-kDa laminin receptor precursor interacts with the prion protein in eukaryotic cells

21 January 2018

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Binding of neural cell adhesion molecules (N-CAMs) to the cellular prion protein

21 January 2018

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Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions

21 January 2018

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Cationic Lipopolyamines Induce Degradation of PrPSc in Scrapie-Infected Mouse Neuroblastoma Cells

21 January 2018

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Diversity of oligosaccharide structures linked to asparagines of the scrapie prion protein

21 January 2018

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Blockade of glycosylation promotes acquisition of scrapie-like properties by the prion protein in cultured cells

21 January 2018

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Extremely rapid folding of the C-terminal domain of the prion protein without kinetic intermediates

21 January 2018

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Role of phosphatidylinositol in attachment of alkaline phosphatase to membranes

21 January 2018

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Membrane environment alters the conformational structure of the recombinant human prion protein

21 January 2018

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Proteasomal Degradation and N-terminal Protease Resistance of the Codon 145 Mutant Prion Protein

21 January 2018

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The Chaperone Protein BiP Binds to a Mutant Prion Protein and Mediates Its Degradation by the Proteasome

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M209942200

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1 December 2017

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