The GABAA receptor alpha 1 subunit Pro174-Asp191 segment is involved in GABA binding and channel gating (Q44295686)

1 December 2017

title

The GABAA receptor alpha 1 subunit Pro174-Asp191 segment is involved in GABA binding and channel gating (English)

1 reference

1 December 2017

J Glen Newell

1

1 reference

1 December 2017

Cynthia Czajkowski

series ordinal

2

1 reference

1 December 2017

language of work or name

English

0 references

publication date

29 January 2003

1 reference

Journal of Biological Chemistry

1 December 2017

published in

1 reference

1 December 2017

volume

278

1 reference

1 December 2017

issue

15

1 reference

1 December 2017

page(s)

13166-13172

1 reference

Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors

1 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Different residues in the GABA(A) receptor alpha 1T60-alpha 1K70 region mediate GABA and SR-95531 actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Arginine residue 120 of the human GABAA receptor alpha 1, subunit is essential for GABA binding and chloride ion current gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

GABAA receptor needs two homologous domains of the beta-subunit for activation by GABA but not by pentobarbital.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

GABA(A) receptor beta 2 Tyr97 and Leu99 line the GABA-binding site. Insights into mechanisms of agonist and antagonist actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Negatively charged amino acid residues in the nicotinic receptor delta subunit that contribute to the binding of acetylcholine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

A mutational analysis of the acetylcholine receptor channel transmitter binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Naturally occurring mutations at the acetylcholine receptor binding site independently alter ACh binding and channel gating.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Preservation and staining of myelinated nerve fibers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Mapping the agonist binding site of the nicotinic acetylcholine receptor. Orientation requirements for activation by covalent agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Mapping the agonist binding site of the nicotinic acetylcholine receptor by cysteine scanning mutagenesis: antagonist footprint and secondary structure prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Identification of a tyrosine in the agonist binding site of the homomeric rho1 gamma-aminobutyric acid (GABA) receptor that, when mutated, produces spontaneous opening

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Potassium currents expressed from Drosophila and mouse eag cDNAs in Xenopus oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Selective labeling of neurotransmitter transporters at the cell surface.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Reactivity of small thiolate anions and cysteine-25 in papain toward methyl methanethiosulfonate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

State-dependent accessibility and electrostatic potential in the channel of the acetylcholine receptor. Inferences from rates of reaction of thiosulfonates with substituted cysteines in the M2 segment of the alpha subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Anxiety over GABA(A) receptor structure relieved by AChBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Restart procedures for the conjugate gradient method

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Models of the extracellular domain of the nicotinic receptors and of agonist- and Ca2+-binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Activation and block of recombinant GABA(A) receptors by pentobarbitone: a single-channel study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

A glia-derived acetylcholine-binding protein that modulates synaptic transmission.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

GABA(A) receptor M2-M3 loop secondary structure and changes in accessibility during channel gating.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Benzodiazepines induce a conformational change in the region of the gamma-aminobutyric acid type A receptor alpha(1)-subunit M3 membrane-spanning segment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

Activation of the nicotinic acetylcholine receptor involves a switch in conformation of the alpha subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

A histidine residue in the extracellular N-terminal domain of the GABA(A) receptor alpha5 subunit regulates sensitivity to inhibition by zinc

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211905200

21 January 2018

Identifiers

DOI

10.1074/JBC.M211905200

1 reference

1 December 2017

1 reference