The role of various Bcl-2 domains in the anti-proliferative effect and modulation of cellular glutathione levels: a prominent role for the BH4 domain (Q44297006)

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English	The role of various Bcl-2 domains in the anti-proliferative effect and modulation of cellular glutathione levels: a prominent role for the BH4 domain	scientific article

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scholarly article

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Europe PubMed Central

1 December 2017

The role of various Bcl-2 domains in the anti-proliferative effect and modulation of cellular glutathione levels: a prominent role for the BH4 domain (English)

1 reference

Europe PubMed Central

1 December 2017

author name string

R W M Hoetelmans

1

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14 May 2020

A L Vahrmeijer

2

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14 May 2020

R L P van Vlierberghe

3

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14 May 2020

R Keijzer

4

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14 May 2020

C J H van de Velde

5

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14 May 2020

G J Mulder

6

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14 May 2020

J H Van Dierendonck

7

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14 May 2020

publication date

1 February 2003

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1 December 2017

Cell Proliferation

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14 May 2020

36

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14 May 2020

1

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14 May 2020

35-44

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14 May 2020

Conversion of Bcl-2 to a Bax-like death effector by caspases

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Bcl-2 and mitochondrial oxygen radicals. New approaches with reactive oxygen species-sensitive probes.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Cleavage of Bcl-2 is an early event in chemotherapy-induced apoptosis of human myeloid leukemia cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Functional dissection of the human Bc12 protein: sequence requirements for inhibition of apoptosis

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Redox state changes in density-dependent regulation of proliferation

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Overexpression of gamma-glutamylcysteine synthetase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappa B and activator protein-1

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Expression of Bcl-2 increases intracellular glutathione by inhibiting methionine-dependent GSH efflux.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Redox regulation of cellular activation

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Protection against hydrogen peroxide cytotoxicity in rat-1 fibroblasts provided by the oncoprotein Bcl-2: maintenance of calcium homoeostasis is secondary to the effect of Bcl-2 on cellular glutathione

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Cell line dependence of Bcl-2-induced alteration of glutathione handling.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Development of resistance to glutathione depletion-induced cell death in CC531 colon carcinoma cells: association with increased expression of bcl-2.

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

BCL-2 and glutathione: alterations in cellular redox state that regulate apoptosis sensitivity

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Bcl-2 expression causes redistribution of glutathione to the nucleus

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Bcl-2 targets the protein kinase Raf-1 to mitochondria

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Bcl-2 and Bax proteins are present in interphase nuclei of mammalian cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Influence of the cellular redox state on NF-kappaB-regulated gene expression

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Bcl-2 counters apoptosis by Bax heterodimerization-dependent and -independent mechanisms in the T-cell lineage

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

N-terminus cleavage of bcl-2 by a novel cellular non-ICE cysteine proteinase

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2184.2003.00252.X

21 January 2018

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

1 reference

https://pubmed.ncbi.nlm.nih.gov/12558659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2-mediated resistance to apoptosis is associated with glutathione-induced inhibition of AP24 activation of nuclear DNA fragmentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12558659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue sulfhydryl groups

1 reference

https://pubmed.ncbi.nlm.nih.gov/12558659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth-associated modifications of low-molecular-weight thiols and protein sulfhydryls in human bronchial fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/12558659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/12558659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 down-regulates the activity of transcription factor NF-kappaB induced upon apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12558659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shift of the cellular oxidation-reduction potential in neural cells expressing Bcl-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12558659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entry

1 reference

https://pubmed.ncbi.nlm.nih.gov/12558659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of transcription factor NF-kappaB activity by Bcl-2 protein in NIH3T3 cells: implication of a novel NF-kappaB p50-Bcl-2 complex for the anti-apoptotic function of Bcl-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12558659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12558659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12558659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12558659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pleiotropic effects of Bcl-2 on transcription factors in T cells: potential role of NF-kappa B p50-p50 for the anti-apoptotic function of Bcl-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12558659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of a bcl-2 transgene reduces proliferation and slows turnover of developing B lymphocytes in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12558659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BCL-2 gene family and the regulation of programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/12558659

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2184.2003.00252.X

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496226&resulttype=core&format=json

14 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496226&resulttype=core&format=json

14 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6496226&resulttype=core&format=json

14 May 2020

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