Identification of a surface charged residue in the S3-S4 linker of the pacemaker (HCN) channel that influences activation gating (Q44312364)

1 December 2017

Identification of a surface charged residue in the S3-S4 linker of the pacemaker (HCN) channel that influences activation gating (English)

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1 December 2017

Charles A Henrikson

1

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1 December 2017

Tian Xue

2

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1 December 2017

Peihong Dong

3

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1 December 2017

Dongpei Sang

4

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1 December 2017

Eduardo Marban

5

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1 December 2017

Ronald A Li

6

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1 December 2017

language of work or name

English

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publication date

11 February 2003

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Journal of Biological Chemistry

1 December 2017

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1 December 2017

278

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1 December 2017

16

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1 December 2017

13647-13654

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Pacemaker mechanisms in cardiac tissue.

1 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Queer current and pacemaker: the hyperpolarization-activated cation current in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Membrane currents underlying activity in frog sinus venosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Potassium current during the pacemaker depolarization in rabbit sinoatrial node cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Molecular identification of a hyperpolarization-activated channel in sea urchin sperm

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

A family of hyperpolarization-activated mammalian cation channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Dominant-negative suppression of HCN1- and HCN2-encoded pacemaker currents by an engineered HCN1 construct: insights into structure-function relationships and multimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Voltage-sensing mechanism is conserved among ion channels gated by opposite voltages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Modulation of the Shaker K(+) channel gating kinetics by the S3-S4 linker

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Periodic perturbations in Shaker K+ channel gating kinetics by deletions in the S3-S4 linker

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Deletion of the S3-S4 linker in the Shaker potassium channel reveals two quenching groups near the outside of S4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Role of the S3-S4 linker in Shaker potassium channel activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Effect of roxithromycin treatment on the endothelial function of Chlamydia pneumoniae seropositive men suffering from peripheral arterial occlusive disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

An external determinant in the S5-P linker of the pacemaker (HCN) channel identified by sulfhydryl modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

The S4-S5 linker couples voltage sensing and activation of pacemaker channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Critical roles of the S3 segment and S3-S4 linker of repeat I in activation of L-type calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Molecular mechanism of cAMP modulation of HCN pacemaker channels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Two pacemaker channels from human heart with profoundly different activation kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Properties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Spectroscopic mapping of voltage sensor movement in the Shaker potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

S4 charges move close to residues in the pore domain during activation in a K channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Voltage-sensing residues in the S4 region of a mammalian K+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Gating charge differences between two voltage-gated K+ channels are due to the specific charge content of their respective S4 regions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Incremental reductions of positive charge within the S4 region of a voltage-gated K+ channel result in corresponding decreases in gating charge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Contribution of the S4 segment to gating charge in the Shaker K+ channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Transmembrane movement of the shaker K+ channel S4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Direct physical measure of conformational rearrangement underlying potassium channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Electrostatic interactions between transmembrane segments mediate folding of Shaker K+ channel subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Voltage-sensing residues in the S2 and S4 segments of the Shaker K+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Electrostatic interactions of S4 voltage sensor in Shaker K+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Mutation of conserved negatively charged residues in the S2 and S3 transmembrane segments of a mammalian K+ channel selectively modulates channel gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Characterizing voltage-dependent conformational changes in the Shaker K+ channel with fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Helical structure of the COOH terminus of S3 and its contribution to the gating modifier toxin receptor in voltage-gated ion channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Functional roles of charged residues in the putative voltage sensor of the HCN2 pacemaker channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Mutations in the S4 domain of a pacemaker channel alter its voltage dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

Molecular basis of the effect of potassium on heterologously expressed pacemaker (HCN) channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211025200

21 January 2018

Identifiers

DOI

10.1074/JBC.M211025200

1 reference

1 December 2017

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