Alpha6beta1 integrin induces proteasome-mediated cleavage of erbB2 in breast cancer cells (Q44313514)

1 December 2017

Alpha6beta1 integrin induces proteasome-mediated cleavage of erbB2 in breast cancer cells (English)

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1 December 2017

Hajime Shimizu

1

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1 December 2017

Takashi Seiki

2

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1 December 2017

Makoto Asada

3

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1 December 2017

Kentaro Yoshimatsu

4

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1 December 2017

Noriyuki Koyama

5

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1 December 2017

language of work or name

English

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publication date

1 February 2003

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1 December 2017

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1 December 2017

22

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1 December 2017

6

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1 December 2017

831-839

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206203

1 December 2017

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cites work

p53 inhibits alpha 6 beta 4 integrin survival signaling by promoting the caspase 3-dependent cleavage of AKT/PKB

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

Cell adhesion regulates ubiquitin-mediated degradation of the platelet-derived growth factor receptor beta

21 January 2018

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Evidence that beta3 integrin-induced Rac activation involves the calpain-dependent formation of integrin clusters that are distinct from the focal complexes and focal adhesions that form as Rac and RhoA become active

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

Colocalization of the p185HER2 oncoprotein and integrin alpha 6 beta 4 in Calu-3 lung carcinoma cells

21 January 2018

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Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

Activation of the p21 pathway of growth arrest and apoptosis by the beta 4 integrin cytoplasmic domain

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

Neu differentiation factor upregulates epidermal migration and integrin expression in excisional wounds.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

Alpha 6 beta 4 and alpha 6 beta 1 integrins associate with ErbB-2 in human carcinoma cell lines.

21 January 2018

1 reference

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Cooperative signaling between alpha(6)beta(4) integrin and ErbB-2 receptor is required to promote phosphatidylinositol 3-kinase-dependent invasion

21 January 2018

1 reference

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Inhibitory role of alpha 6 beta 4-associated erbB-2 and phosphoinositide 3-kinase in keratinocyte haptotactic migration dependent on alpha 3 beta 1 integrin

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

Cell adhesion protects c-Raf-1 against ubiquitin-dependent degradation by the proteasome

21 January 2018

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Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

Degradation process of ligand-stimulated platelet-derived growth factor beta-receptor involves ubiquitin-proteasome proteolytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

Changes in expression of alpha 6/beta 4 integrin heterodimer in primary and metastatic breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

Release of cAMP gating by the alpha6beta4 integrin stimulates lamellae formation and the chemotactic migration of invasive carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3'-kinase to the integrin signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

Laminin activates the p185HER2 oncoprotein and mediates growth inhibition of breast carcinoma cells

21 January 2018

1 reference

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Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology

21 January 2018

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Extracellular matrix composition determines the transcriptional response to epidermal growth factor receptor activation

21 January 2018

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Urokinase-type plasminogen activator binding to its receptor stimulates tumor cell migration by enhancing integrin-mediated signal transduction

21 January 2018

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HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

Re-expression of the alpha 2 beta 1 integrin abrogates the malignant phenotype of breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

Stimulation of beta1-integrin function by epidermal growth factor and heregulin-beta has distinct requirements for erbB2 but a similar dependence on phosphoinositide 3-OH kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Signal transduction pathways activated and required for mammary carcinogenesis in response to specific oncogenes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Cell attachment to the extracellular matrix induces proteasomal degradation of p21(CIP1) via Cdc42/Rac1 signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Down-regulation of MET, the receptor for hepatocyte growth factor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Integrin alphavbeta3 promotes anchorage-dependent apoptosis in human intestinal carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Extracellular matrix selectively modulates the response of mammary epithelial cells to different soluble signaling ligands

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion-dependent cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Increased levels of alpha6 integrins are associated with the metastatic phenotype of human breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Effects of oncogenic ErbB2 on G1 cell cycle regulators in breast tumour cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Low expression of beta 1, alpha 2 and alpha 3 subunits of VLA integrins in malignant mammary tumours

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

A novel function for the tumor suppressor p16(INK4a): induction of anoikis via upregulation of the alpha(5)beta(1) fibronectin receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Alphavbeta3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Integrin alpha 5 beta 1 expression negatively regulates cell growth: reversal by attachment to fibronectin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Integrin alpha6beta1 role in metastatic behavior of human pancreatic carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206203

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1206203

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Dimensions Publication ID

1 December 2017

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