Unusual function of the activation loop in the protein kinase DYRK1A. (Q44327100)

2 December 2017

Unusual function of the activation loop in the protein kinase DYRK1A. (English)

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2 December 2017

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Joachim Grötzinger

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author name string

Stephan Wiechmann

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2 December 2017

Hanna Czajkowska

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2 December 2017

Katrin de Graaf

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2 December 2017

Joachim Grötzinger

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2 December 2017

language of work or name

English

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publication date

1 March 2003

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Biochemical and Biophysical Research Communications

2 December 2017

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2 December 2017

302

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2 December 2017

2

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2 December 2017

403-408

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Structural and functional characteristics of Dyrk, a novel subfamily of protein kinases with dual specificity.

2 December 2017

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Loss of Ras activity in Saccharomyces cerevisiae is suppressed by disruptions of a new kinase gene, YAKI, whose product may act downstream of the cAMP-dependent protein kinase

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Pom1p, a fission yeast protein kinase that provides positional information for both polarized growth and cytokinesis.

7 January 2021

1 reference

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Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII

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1 reference

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Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases

7 January 2021

1 reference

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Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases

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A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region

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Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome

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1 reference

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Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.

7 January 2021

1 reference

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DYRK3 activation, engagement of protein kinase A/cAMP response element-binding protein, and modulation of progenitor cell survival

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Fission yeast Pom1p kinase activity is cell cycle regulated and essential for cellular symmetry during growth and division

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Specificity determinants of substrate recognition by the protein kinase DYRK1A

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Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation

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The structure of Sky1p reveals a novel mechanism for constitutive activity

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Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors

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Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

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A role for autophosphorylation revealed by activated alleles of FUS3, the yeast MAP kinase homolog

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Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2

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A new expression cloning strategy for isolation of substrate-specific kinases by using phosphorylation site-specific antibody

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The structure of phosphorylated p38gamma is monomeric and reveals a conserved activation-loop conformation

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Crystal structure of human protein kinase CK2: insights into basic properties of the CK2 holoenzyme

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Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity

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The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification 1

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inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-291X(03)00148-7

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2 December 2017

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