Statin effects on cholesterol micro-domains in brain plasma membranes (Q44356716)

2 December 2017

title

Statin effects on cholesterol micro-domains in brain plasma membranes (English)

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2 December 2017

Christopher Kirsch

1

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2 December 2017

Gunter P Eckert

series ordinal

2

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2 December 2017

Walter E Mueller

series ordinal

3

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2 December 2017

language of work or name

English

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publication date

1 March 2003

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2 December 2017

published in

Biochemical Pharmacology

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2 December 2017

volume

65

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2 December 2017

issue

5

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2 December 2017

page(s)

843-856

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Amyloid and lipids in the pathology of Alzheimer disease.

2 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

The role of cholesterol in the biosynthesis of beta-amyloid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Recent advances in brain cholesterol dynamics: transport, domains, and Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Apolipoprotein E-4 gene dose in clinically diagnosed Alzheimer's disease: prevalence, plasma cholesterol levels and cerebrovascular change.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Membrane lipids, selectively diminished in Alzheimer brains, suggest synapse loss as a primary event in early-onset form (type I) and demyelination in late-onset form (type II).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Evidence for changes in the Alzheimer's disease brain cortical membrane structure mediated by cholesterol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Cholesterol-dependent formation of GM1 ganglioside-bound amyloid beta-protein, an endogenous seed for Alzheimer amyloid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Alzheimer's disease: a central role for amyloid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

beta-Amyloid protein amplifies calcium signalling in central neurons from the adult mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Molecular mechanism of neurodegeneration induced by Alzheimer's beta-amyloid protein: channel formation and disruption of calcium homeostasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Membrane-disordering effects of beta-amyloid peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

A comparison of clinical outcome studies among cholesterol-lowering agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Statins and the risk of dementia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Hydrophilicity/lipophilicity: relevance for the pharmacology and clinical effects of HMG-CoA reductase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

In vivo and in vitro blood-brain barrier transport of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Concentrations of pravastatin and lovastatin in cerebrospinal fluid in healthy subjects.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Carrier-mediated uptake of pravastatin by rat hepatocytes in primary culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Cholesterol metabolism in the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Cholesterol, A beta and Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Alzheimer's disease. Bad for the heart, bad for the mind?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Cholesterol modulation as an emerging strategy for the treatment of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

A fluid connection: cholesterol and Abeta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Statins in the 21st century: end of the simple story?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Clinical pharmacokinetics of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Non-lipid-related effects of statins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Use of statins in CNS disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Potential neurological value of statins increases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

How cells handle cholesterol.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Cholesterol domains in biological membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Amyloid beta peptide alters intracellular vesicle trafficking and cholesterol homeostasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Differential effects of lovastatin treatment on brain cholesterol levels in normal and apoE-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: evidence that simvastatin affects cholesterol metabolism in the human brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Comparative toxicity of high doses of vastatins currently used by clinicians, in CD-1 male mice fed with a hypercholesterolemic diet

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Effects of aging and beta-amyloid on the properties of brain synaptic and mitochondrial membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Transmembrane distribution of sterol in the human erythrocyte

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Modulation of ATPase activities of human erythrocyte membranes by free fatty acids or phospholipase A2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Recent advances in membrane cholesterol domain dynamics and intracellular cholesterol trafficking

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Transbilayer effects of ethanol on fluidity of brain membrane leaflets.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Location of diphenylhexatriene (DPH) and its derivatives within membranes: comparison of different fluorescence quenching analyses of membrane depth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Use of fluorescent probes to monitor molecular order and motions within liposome bilayers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Polarization of the fluorescence of macromolecules. I. Theory and experimental method

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Plasma membrane lipid composition modulates action of anesthetics.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Charged anaesthetics alter LM-fibroblast plasma-membrane enzymes by selective fluidization of inner or outer membrane leaflets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Temperature, pressure and cholesterol effects on bilayer fluidity; a comparison of pyrene excimer/monomer ratios with the steady-state fluorescence polarization of diphenylhexatriene in liposomes and microsomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Lipid rafts of purified mouse brain synaptosomes prepared with or without detergent reveal different lipid and protein domains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Cholesterol attenuates the membrane perturbing properties of beta-amyloid peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Determination of lipid phosphorus in the nanomolar range

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Lack of predictability of classical animal models for hypolipidemic activity: a good time for mice?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Lipid rafts and signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Compartmentalization of beta-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Requirement for mevalonate in acetylated LDL induction of cholesterol esterification in macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Accumulation and aggregation of amyloid beta-protein in late endosomes of Niemann-pick type C cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Cholesterol modulates the membrane-disordering effects of beta-amyloid peptides in the hippocampus: specific changes in Alzheimer's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Transbilayer distribution of cholesterol is modified in brain synaptic plasma membranes of knockout mice deficient in the low-density lipoprotein receptor, apolipoprotein E, or both proteins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Essential fatty acids as possible mediators of the actions of statins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Apolipoprotein-E allele-specific regulation of nitric oxide production.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Low-density lipoprotein receptor on endothelium of brain capillaries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Cholesterol and Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

A new role for apolipoprotein E: modulating transport of polyunsaturated phospholipid molecular species in synaptic plasma membranes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Cholesterol depletion induces large scale domain segregation in living cell membranes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

Recent advances in membrane microdomains: rafts, caveolae, and intracellular cholesterol trafficking

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2802%2901654-4

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(02)01654-4

1 reference

2 December 2017

1 reference