The nucleotide-binding domains of P-glycoprotein. Functional symmetry in the isolated domain demonstrated by N-ethylmaleimide labelling (Q44373782)

2 December 2017

title

The nucleotide-binding domains of P-glycoprotein. Functional symmetry in the isolated domain demonstrated by N-ethylmaleimide labelling (English)

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2 December 2017

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2 December 2017

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2 December 2017

Georgina Berridge

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2 December 2017

Jennifer A Walker

series ordinal

2

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2 December 2017

language of work or name

English

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publication date

1 April 2003

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2 December 2017

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2 December 2017

volume

270

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2 December 2017

issue

7

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2 December 2017

page(s)

1483-1492

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ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans

2 December 2017

cites work

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The catalytic cycle of P-glycoprotein

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Kinetics of Steady-state Currents and Charge Movements Associated with the Rat Na+/Glucose Cotransporter

21 January 2018

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Both ATP sites of human P-glycoprotein are essential but not symmetric

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Structural and functional asymmetry of the nucleotide-binding domains of P-glycoprotein investigated by attenuated total reflection Fourier transform infrared spectroscopy

21 January 2018

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Investigation of the role of glutamine-471 and glutamine-1114 in the two catalytic sites of P-glycoprotein

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Conserved walker A Ser residues in the catalytic sites of P-glycoprotein are critical for catalysis and involved primarily at the transition state step.

21 January 2018

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Comparison of the functional characteristics of the nucleotide binding domains of multidrug resistance protein 1.

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Allosteric interactions between the two non-equivalent nucleotide binding domains of multidrug resistance protein MRP1.

21 January 2018

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Walker A lysine mutations of TAP1 and TAP2 interfere with peptide translocation but not peptide binding.

21 January 2018

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Distinct functions of the ATP binding cassettes of transporters associated with antigen processing: a mutational analysis of Walker A and B sequences

21 January 2018

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Functional asymmetry of the two nucleotide binding domains in the ABC transporter Ste6.

21 January 2018

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The two nucleotide-binding domains of cystic fibrosis transmembrane conductance regulator (CFTR) have distinct functions in controlling channel activity

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Analysis of MDR1 P-glycoprotein conformational changes in permeabilized cells using differential immunoreactivity.

21 January 2018

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Conformational changes of P-glycoprotein by nucleotide binding

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Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle

21 January 2018

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Crystal structures of the MJ1267 ATP binding cassette reveal an induced-fit effect at the ATPase active site of an ABC transporter

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The crystal structure of the MJ0796 ATP-binding cassette. Implications for the structural consequences of ATP hydrolysis in the active site of an ABC transporter

21 January 2018

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The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism

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Crystal structure of the ATP-binding subunit of an ABC transporter

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Comparative protein modelling by satisfaction of spatial restraints

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Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing

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Homology modeling, model and software evaluation: three related resources

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

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Binding of steroid modulators to recombinant cytosolic domain from mouse P-glycoprotein in close proximity to the ATP site.

21 January 2018

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Sequence requirements of the ATP-binding site within the C-terminal nucleotide-binding domain of mouse P-glycoprotein: structure-activity relationships for flavonoid binding

21 January 2018

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Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis

21 January 2018

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Expression and purification of the first nucleotide-binding domain and linker region of human multidrug resistance gene product: comparison of fusions to glutathione S-transferase, thioredoxin and maltose-binding protein

21 January 2018

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Nucleotide triphosphatase activity of the N-terminal nucleotide-binding domains of the multidrug resistance proteins P-glycoprotein and MRP1.

21 January 2018

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Functional asymmetry of the ATP-binding-cassettes of the ABC transporter TAP is determined by intrinsic properties of the nucleotide binding domains

21 January 2018

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Three-dimensional structure by cryo-electron microscopy of YvcC, an homodimeric ATP-binding cassette transporter from Bacillus subtilis

21 January 2018

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Non-equivalent cooperation between the two nucleotide-binding folds of P-glycoprotein

21 January 2018

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10.1046/J.1432-1033.2003.03514.X

21 January 2018

Identifiers

DOI

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release_kylpzystnvfnlhixlgo7iuxmci

2 December 2017

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24 November 2022

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