Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis (Q44381508)

2 December 2017

Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis (English)

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2 December 2017

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3

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2 December 2017

Lisa A Madge

1

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2 December 2017

Jie-Hui Li

series ordinal

2

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2 December 2017

Jordan S Pober

series ordinal

4

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2 December 2017

language of work or name

English

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publication date

27 March 2003

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Journal of Biological Chemistry

2 December 2017

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2 December 2017

278

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2 December 2017

23

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2 December 2017

21295-21306

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The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

2 December 2017

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Inhibition of death receptor signals by cellular FLIP

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

An induced proximity model for caspase-8 activation.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Pro-caspase-3 is a major physiologic target of caspase-8.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Dimerization properties of human BAD. Identification of a BH-3 domain and analysis of its binding to mutant BCL-2 and BCL-XL proteins

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Two CD95 (APO-1/Fas) signaling pathways

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Interferon-gamma augments CD95(APO-1/Fas) and pro-caspase-8 expression and sensitizes human vascular endothelial cells to CD95-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

NF-kappaB signals induce the expression of c-FLIP.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Destabilizing influences in apoptosis: sowing the seeds of IAP destruction

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

A constitutive cytoprotective pathway protects endothelial cells from lipopolysaccharide-induced apoptosis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Cathepsin B acts as a dominant execution protease in tumor cell apoptosis induced by tumor necrosis factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

Sensitization to death receptor cytotoxicity by inhibition of fas-associated death domain protein (FADD)/caspase signaling. Requirement of cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

Cathepsin B knockout mice are resistant to tumor necrosis factor-alpha-mediated hepatocyte apoptosis and liver injury: implications for therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212837200

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

Kinase regulation in inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

Cytoprotection of human umbilical vein endothelial cells against apoptosis and CTL-mediated lysis provided by caspase-resistant Bcl-2 without alterations in growth or activation responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

Noncaspase proteases in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

Triggering caspase-independent cell death to combat cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

Cathepsin B contributes to TNF-alpha-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

Tumor necrosis factor- induces adhesion molecule expression through the sphingosine kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

Lysosomal protease pathways to apoptosis. Cleavage of bid, not pro-caspases, is the most likely route

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212837200

21 January 2018

Identifiers

DOI

10.1074/JBC.M212837200

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2 December 2017

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