Arcuate Nucleus-Specific Leptin Receptor Gene Therapy Attenuates the Obesity Phenotype of Koletsky (fak/fak) Rats (Q44405123)

2 December 2017

title

Arcuate nucleus-specific leptin receptor gene therapy attenuates the obesity phenotype of Koletsky (fa(k)/fa(k)) rats (English)

1 reference

https://api.crossref.org/works/10.1210/EN.2002-0115

2 December 2017

Arcuate Nucleus-Specific Leptin Receptor Gene Therapy Attenuates the Obesity Phenotype of Koletsky (fak/fak) Rats (English)

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24 December 2023

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https://api.crossref.org/works/10.1210/EN.2002-0115

24 December 2023

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Christopher J. Rhodes

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12697710

24 December 2023

author name string

Gregory J. Morton

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12697710

24 December 2023

Kevin D. Niswender

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12697710

24 December 2023

Martin G. Myers

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12697710

24 December 2023

James E. Blevins

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12697710

24 December 2023

Denis G. Baskin

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12697710

24 December 2023

Michael W. Schwartz

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12697710

24 December 2023

language of work or name

English

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publication date

1 May 2003

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full work available at URL

2 December 2017

published in

Endocrinology

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2 December 2017

volume

144

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2 December 2017

issue

5

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2 December 2017

page(s)

2016-2024

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Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector

2 December 2017

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Identification and expression cloning of a leptin receptor, OB-R

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Phenotype of fatty due to Gln269Pro mutation in the leptin receptor (Lepr).

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Nonsense mutation of leptin receptor in the obese spontaneously hypertensive Koletsky rat

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Phenotype of the obese Koletsky (f) rat due to Tyr763Stop mutation in the extracellular domain of the leptin receptor (Lepr): evidence for deficient plasma-to-CSF transport of leptin in both the Zucker and Koletsky obese rat.

24 December 2023

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Congenital leptin deficiency is associated with severe early-onset obesity in humans

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A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

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Divergent signaling capacities of the long and short isoforms of the leptin receptor

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The leptin receptor activates janus kinase 2 and signals for proliferation in a factor-dependent cell line

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Anatomic localization of alternatively spliced leptin receptors (Ob-R) in mouse brain and other tissues.

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Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice

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Feeding effects of hypothalamic injection of melanocortin 4 receptor ligands

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Leptin increases hypothalamic pro-opiomelanocortin mRNA expression in the rostral arcuate nucleus.

24 December 2023

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Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and [corrected] in ob/ob and db/db mice, but is stimulated by leptin

24 December 2023

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A C-terminal fragment of Agouti-related protein increases feeding and antagonizes the effect of alpha-melanocyte stimulating hormone in vivo

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Regulation of leptin receptor and NPY gene expression in hypothalamus of leptin-treated obese (ob/ob) and cold-exposed lean mice

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Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus

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The arcuate nucleus as a primary site of satiety effect of leptin in rats

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24 December 2023

Identifiers

DOI

10.1210/EN.2002-0115

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2 December 2017

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