Stepwise cumulation of RUNX3 methylation mediated by Helicobacter pylori infection contributes to gastric carcinoma progression (Q44456898)

3 December 2017

Stepwise cumulation of RUNX3 methylation mediated by Helicobacter pylori infection contributes to gastric carcinoma progression (English)

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Helicobacter pylori infectious disease

3 December 2017

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Xiao-Xiao Lu

1

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3 December 2017

Jiang-Liu Yu

2

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3 December 2017

Li-Sha Ying

3

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3 December 2017

Jing Han

4

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3 December 2017

Shi Wang

5

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3 December 2017

Qi-Ming Yu

6

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3 December 2017

Xin-Bao Wang

7

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3 December 2017

Xian-Hua Fang

8

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3 December 2017

Zhi-Qiang Ling

9

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3 December 2017

language of work or name

English

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publication date

10 May 2012

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3 December 2017

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3 December 2017

118

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3 December 2017

22

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3 December 2017

5507-5517

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3 December 2017

Cancer statistics, 2010

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Helicobacter pylori infection and gastric cardia cancer: systematic review and meta-analysis

21 January 2018

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Cancer incidence and incidence rates in Japan in 2004: based on data from 14 population-based cancer registries in the Monitoring of Cancer Incidence in Japan (MCIJ) Project

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Gene expression profiling reveals sequential changes in gastric tubular adenoma and carcinoma in situ

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Epidemiological review of gastric cancer in India

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Helicobacter pylori infection in relation to gastric cancer progression

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Multifocal atrophic gastritis and gastric carcinoma

21 January 2018

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Pathology of gastric intestinal metaplasia: clinical implications

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Nitrative DNA damage in inflammation and its possible role in carcinogenesis

21 January 2018

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Pathology and genetics of familial gastric cancer

21 January 2018

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Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells

21 January 2018

1 reference

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Chromatin and DNA methylation dynamics of Helicobacter pylori-induced COX-2 activation.

21 January 2018

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Novel risk markers for gastric cancer screening: Present status and future prospects

21 January 2018

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21 January 2018

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Frequent inactivation of RUNX3 by promoter hypermethylation and protein mislocalization in oral squamous cell carcinomas

21 January 2018

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The expression of RUNX3 in colorectal cancer is associated with disease stage and patient outcome.

21 January 2018

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RUNX3 inactivation by frequent promoter hypermethylation and protein mislocalization constitute an early event in breast cancer progression.

21 January 2018

1 reference

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RUNX3 modulates DNA damage-mediated phosphorylation of tumor suppressor p53 at Ser-15 and acts as a co-activator for p53.

21 January 2018

1 reference

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Loss of RUNX3 expression by histone deacetylation is associated with biliary tract carcinogenesis

21 January 2018

1 reference

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Frequent downregulation of the runt domain transcription factors RUNX1, RUNX3 and their cofactor CBFB in gastric cancer.

21 January 2018

1 reference

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RUNX3 directly interacts with intracellular domain of Notch1 and suppresses Notch signaling in hepatocellular carcinoma cells

21 January 2018

1 reference

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Hypermethylation downregulates Runx3 gene expression and its restoration suppresses gastric epithelial cell growth by inducing p27 and caspase3 in human gastric cancer.

21 January 2018

1 reference

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Loss of Runx3 is a key event in inducing precancerous state of the stomach

21 January 2018

1 reference

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New insights into the inactivation of gastric tumor suppressor RUNX3: the role of H. pylori infection

21 January 2018

1 reference

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Helicobacter pylori CagA targets gastric tumor suppressor RUNX3 for proteasome-mediated degradation

21 January 2018

1 reference

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Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm

21 January 2018

1 reference

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Causal relationship between the loss of RUNX3 expression and gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.27604

RUNX3 is multifunctional in carcinogenesis of multiple solid tumors

21 January 2018

1 reference

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Helicobacter pylori CagA inhibits the expression of Runx3 via Src/MEK/ERK and p38 MAPK pathways in gastric epithelial cell

21 January 2018

1 reference

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MTHFR C677T polymorphism and differential methylation status in gastric cancer: an association with Helicobacter pylori infection

21 January 2018

1 reference

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Helicobacter pylori infection promotes methylation and silencing of trefoil factor 2, leading to gastric tumor development in mice and humans.

21 January 2018

1 reference

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Helicobacter pylori and EBV in gastric carcinomas: methylation status and microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.27604

Helicobacter pylori Infection, Intestinal Metaplasia, and Gastric Cancer Risk in Eastern Siberia

21 January 2018

1 reference

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Relationship between cagA-positive Helicobacter pylori infection and risk of gastric cancer: a case control study in Porto Alegre, RS, Brazil

21 January 2018

1 reference

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7 January 2021

Aberrant DNA Methylation in Non-Neoplastic Gastric Mucosa of H. Pylori Infected Patients and Effect of Eradication

1 reference

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7 January 2021

Persistence of a component of DNA methylation in gastric mucosae after Helicobacter pylori eradication

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7 January 2021

Global DNA hypomethylation is an early event in Helicobacter pylori-related gastric carcinogenesis

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7 January 2021

Expression of RUNX3 protein in human lung adenocarcinoma: implications for tumor progression and prognosis

1 reference

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7 January 2021

Frequent silencing of RUNX3 in esophageal squamous cell carcinomas is associated with radioresistance and poor prognosis

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7 January 2021

RUNX3 methylation and expression associated with advanced precancerous gastric lesions in a Chinese population

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7 January 2021

Frequent loss of heterozygosity of the long arm of chromosome 7 is closely associated with progression of human gastric carcinomas

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7 January 2021

Microsatellite instability with promoter methylation and silencing of hMLH1 can regionally occur during progression of gastric carcinoma

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7 January 2021

Helicobacter pylori causes runx3 gene methylation and its loss of expression in gastric epithelial cells, which is mediated by nitric oxide produced by macrophages

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7 January 2021

Identifiers

DOI

10.1002/CNCR.27604

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3 December 2017

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