The role of 2',3'-unsaturation on the antiviral activity of anti-HIV nucleosides against 3TC-resistant mutant (M184V). (Q44461787)

3 December 2017

title

The role of 2',3'-unsaturation on the antiviral activity of anti-HIV nucleosides against 3TC-resistant mutant (M184V). (English)

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3 December 2017

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ChEBI release 2020-05-28

3

Chung K Chu

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3 December 2017

Hyunah Choo

1

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3 December 2017

Youhoon Chong

series ordinal

2

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3 December 2017

language of work or name

English

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publication date

1 June 2003

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Bioorganic & Medicinal Chemistry Letters

3 December 2017

published in

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3 December 2017

volume

13

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3 December 2017

issue

12

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3 December 2017

page(s)

1993-1996

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Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase

3 December 2017

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Anti-human immunodeficiency virus activity and cellular metabolism of a potential prodrug of the acyclic nucleoside phosphonate 9-R-(2-phosphonomethoxypropyl)adenine (PMPA), Bis(isopropyloxymethylcarbonyl)PMPA

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Novel mutation (V75T) in human immunodeficiency virus type 1 reverse transcriptase confers resistance to 2',3'-didehydro-2',3'-dideoxythymidine in cell culture

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DPC 817: a cytidine nucleoside analog with activity against zidovudine- and lamivudine-resistant viral variants

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Synthesis, anti-HIV activity, and molecular mechanism of drug resistance of L-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides

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Stereoselective synthesis and antiviral activity of D-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides

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1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity

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Molecular mechanism of DApd/DXG against zidovudine- and lamivudine- drug resistant mutants: a molecular modelling approach

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Molecular modeling approach to understanding the mode of action of L-nucleosides as antiviral agents

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

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A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

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Organic Fluorine Hardly Ever Accepts Hydrogen Bonds

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Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.

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Understanding the unique mechanism of L-FMAU (clevudine) against hepatitis B virus: molecular dynamics studies

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7 January 2021

10.1016/S0960-894X(03)00330-5

Identifiers

DOI

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3 December 2017

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