Compromised incision of oxidized pyrimidines in liver mitochondria of mice deficient in NTH1 and OGG1 glycosylases. (Q44486177)

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5 November 2019

title

Compromised incision of oxidized pyrimidines in liver mitochondria of mice deficient in NTH1 and OGG1 glycosylases (English)

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5 November 2019

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4

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5

Vilhelm A Bohr

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5 November 2019

author name string

Bensu Karahalil

series ordinal

1

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5 November 2019

Nadja C de Souza-Pinto

series ordinal

2

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5 November 2019

Jason L Parsons

series ordinal

3

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5 November 2019

language of work or name

English

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publication date

22 June 2003

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Journal of Biological Chemistry

5 November 2019

published in

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5 November 2019

volume

278

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5 November 2019

issue

36

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5 November 2019

page(s)

33701-33707

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Mitochondria, oxygen free radicals, disease and ageing

5 November 2019

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Base excision of oxidative purine and pyrimidine DNA damage in Saccharomyces cerevisiae by a DNA glycosylase with sequence similarity to endonuclease III from Escherichia coli

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Purification and characterization of human NTH1, a homolog of Escherichia coli endonuclease III. Direct identification of Lys-212 as the active nucleophilic residue

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Novel substrates of Escherichia coli nth protein and its kinetics for excision of modified bases from DNA damaged by free radicals

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DNA substrates containing defined oxidative base lesions and their application to study substrate specificities of base excision repair enzymes

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Cell-cycle regulation, intracellular sorting and induced overexpression of the human NTH1 DNA glycosylase involved in removal of formamidopyrimidine residues from DNA

21 January 2018

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Excision of products of oxidative DNA base damage by human NTH1 protein.

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Saccharomyces cerevisiae Ntg1p and Ntg2p: broad specificity N-glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria

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Mitochondrial targeting of human DNA glycosylases for repair of oxidative DNA damage

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Novel nuclear and mitochondrial glycosylases revealed by disruption of the mouse Nth1 gene encoding an endonuclease III homolog for repair of thymine glycols

21 January 2018

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Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

21 January 2018

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Repair of dihydrouracil supported by base excision repair in mNTH1 knock-out cell extracts.

21 January 2018

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An oxidative damage-specific endonuclease from rat liver mitochondria.

21 January 2018

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Targeted deletion of mNth1 reveals a novel DNA repair enzyme activity.

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DNA damage, mutation and fine structure DNA repair in aging.

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HPLC isolation and mass spectrometric characterization of two isomers of thymine glycols in oligodeoxynucleotides

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Quantitative measurement of the diastereoisomers of cis thymidine glycol in gamma-irradiated DNA.

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Comparison of substrate specificities of Escherichia coli endonuclease III and its mouse homologue (mNTH1) using defined oligonucleotide substrates.

21 January 2018

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Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA

21 January 2018

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A novel human DNA glycosylase that removes oxidative DNA damage and is homologous to Escherichia coli endonuclease VIII

21 January 2018

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Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M301617200

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12819227%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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