Role of nuclear and cytoplasmic localization in the tumour-suppressor activity of the von Hippel-Lindau protein. (Q44488188)

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5 November 2019

title

Role of nuclear and cytoplasmic localization in the tumour-suppressor activity of the von Hippel-Lindau protein (English)

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5 November 2019

1

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5 November 2019

author name string

Ben J Roberts

series ordinal

2

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5 November 2019

language of work or name

English

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publication date

1 June 2003

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5 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12821933%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

volume

22

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5 November 2019

issue

26

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5 November 2019

page(s)

3992-3997

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1206683

5 November 2019

exact match

0 references

cites work

Role of exon 2-encoded beta -domain of the von Hippel-Lindau tumor suppressor protein

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Von Hippel-Lindau disease: clinical and molecular perspectives

21 January 2018

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Sequence determinants in hypoxia-inducible factor-1alpha for hydroxylation by the prolyl hydroxylases PHD1, PHD2, and PHD3.

21 January 2018

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The von Hippel-Lindau tumor suppressor protein

21 January 2018

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Nuclear/cytoplasmic localization of the von Hippel-Lindau tumor suppressor gene product is determined by cell density

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206683

The von Hippel-Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal

21 January 2018

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Degradation of the basic helix-loop-helix/Per-ARNT-Sim homology domain dioxin receptor via the ubiquitin/proteasome pathway

21 January 2018

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Hypoxia-inducible factor-1 alpha (HIF-1 alpha) escapes O(2)-driven proteasomal degradation irrespective of its subcellular localization: nucleus or cytoplasm

21 January 2018

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7 January 2021

Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease.

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7 January 2021

VHL induces renal cell differentiation and growth arrest through integration of cell-cell and cell-extracellular matrix signaling

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7 January 2021

Inhibition of transcription elongation by the VHL tumor suppressor protein

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7 January 2021

Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1alpha

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7 January 2021

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

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7 January 2021

Oxygen-dependent ubiquitination and degradation of hypoxia-inducible factor requires nuclear-cytoplasmic trafficking of the von Hippel-Lindau tumor suppressor protein

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7 January 2021

von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF.

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7 January 2021

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

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7 January 2021

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

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7 January 2021

The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells

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7 January 2021

Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein

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7 January 2021

The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix

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7 January 2021

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

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7 January 2021