Nanomolar affinity small molecule correctors of defective Delta F508-CFTR chloride channel gating. (Q44495355)

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5 November 2019

title

Nanomolar affinity small molecule correctors of defective Delta F508-CFTR chloride channel gating (English)

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5 November 2019

7

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5 November 2019

R. Kiplin Guy

3

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5 November 2019

Tonghui Ma

5

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5 November 2019

Nicoletta Pedemonte

10

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5 November 2019

Luis Galietta

11

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5 November 2019

2

Anang A Shelat

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5 November 2019

author name string

Hong Yang

1

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5 November 2019

Vadiraj S Gopinath

4

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5 November 2019

Kai Du

6

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5 November 2019

Alessandro Taddei

8

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5 November 2019

Chiara Folli

9

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5 November 2019

A S Verkman

12

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language of work or name

English

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publication date

27 June 2003

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Journal of Biological Chemistry

5 November 2019

published in

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volume

278

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issue

37

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5 November 2019

page(s)

35079-35085

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Cystic fibrosis: a worldwide analysis of CFTR mutations--correlation with incidence data and application to screening

5 November 2019

cites work

1 reference

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Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

21 January 2018

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Glycerol reverses the misfolding phenotype of the most common cystic fibrosis mutation.

21 January 2018

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Chemical chaperones correct the mutant phenotype of the delta F508 cystic fibrosis transmembrane conductance regulator protein

21 January 2018

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Conformational and temperature-sensitive stability defects of the delta F508 cystic fibrosis transmembrane conductance regulator in post-endoplasmic reticulum compartments.

21 January 2018

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Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells

21 January 2018

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Life extension in Drosophila by feeding a drug.

21 January 2018

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Deletion of phenylalanine 508 causes attenuated phosphorylation-dependent activation of CFTR chloride channels

21 January 2018

1 reference

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Chloride Conductance Expressed by ΔF508 and Other Mutant CFTRs In Xenopus Oocytes

21 January 2018

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High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening

21 January 2018

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Green fluorescent protein-based halide indicators with improved chloride and iodide affinities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M303098200

Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds

21 January 2018

1 reference

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

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Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M303098200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12832418%20AND%20SRC:MED&resulttype=core&format=json

release_75qcgah6hvf5ppcmybjp7q7pqu

5 November 2019

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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