Rational design of alkylene-linked bis-pyridiniumaldoximes as improved acetylcholinesterase reactivators (Q44499051)

3 December 2017

title

Rational design of alkylene-linked bis-pyridiniumaldoximes as improved acetylcholinesterase reactivators (English)

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3 December 2017

1

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3 December 2017

Thomas M Kollmeyer

2

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3 December 2017

Feng Hong

3

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3 December 2017

Jong-Cheol Lee

4

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3 December 2017

Pamela I Hammond

5

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3 December 2017

Sharie P Haugabouk

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3 December 2017

Stephen Brimijoin

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3 December 2017

publication date

1 June 2003

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3 December 2017

published in

Chemistry and Biology

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3 December 2017

volume

10

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3 December 2017

issue

6

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3 December 2017

page(s)

491-502

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A powerful reactivator of alkylphosphate-inhibited acetylcholinesterase

3 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

The pH dependence of dealkylation in soman-inhibited cholinesterases and their mutants: further evidence for a push-pull mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Small molecular products of dealkylation in soman-inhibited electric eel acetylcholinesterase.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Effects of some mono- and bisquaternary ammonium compounds on the reactivatability of soman-inhibited human acetylcholinesterase in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

The treatment of Soman poisoning and its perspectives.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

New potent reactivators of acetocholinesterase inhibited by tetraethyl pyrophosphate.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Protection by Oximes of bis-Pyridinium Ions against Lethal Diisopropyl Phosphonofluoridate Poisoning

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Molecular complementariness as basis for reactivation of alkyl phosphate-inhibited enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Synthesis and biological activity of conformationally controlled 2-PAM derivatives

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

A crystallographic study of N-methyl-pyridine-2-aldoxime (2-PAM) halides

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Highly potent, selective, and low cost bis-tetrahydroaminacrine inhibitors of acetylcholinesterase. Steps toward novel drugs for treating Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Quaternary salts of 2-[(hydroxyimino)methyl]imidazole. 3. Synthesis and evaluation of (alkenyloxy)-, (alkynyloxy)-, and (aralkyloxy)methyl quaternarized 2-[(hydroxyimino)methyl]-1-alkylimidazolium halides as reactivators and therapy for soman intoxi

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Locally accessible conformations of proteins: multiple molecular dynamics simulations of crambin

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Assessing equilibration and convergence in biomolecular simulations

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Absolute comparison of simulated and experimental protein-folding dynamics

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Simulation of folding of a small alpha-helical protein in atomistic detail using worldwide-distributed computing

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Reaction Products of Acetylcholinesterase and VX Reveal a Mobile Histidine in the Catalytic Triad

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Aromatic rings act as hydrogen bond acceptors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

The Protein Data Bank: a computer-based archival file for macromolecular structures

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

The Protein Data Bank

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Characterization of O,O-diethylphosphoryl oximes as inhibitors of cholinesterases and substrates of phosphotriesterases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Acetylcholinesterase complexed with bivalent ligands related to huperzine a: experimental evidence for species-dependent protein-ligand complementarity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Kinetic and structural studies on the interaction of cholinesterases with the anti-Alzheimer drug rivastigmine

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

A new and rapid colorimetric determination of acetylcholinesterase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

CHARMM: A program for macromolecular energy, minimization, and dynamics calculations

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Density-functional thermochemistry. III. The role of exact exchange

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

EUDOC: a computer program for identification of drug interaction sites in macromolecules and drug leads from chemical databases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Molecular dynamics with coupling to an external bath

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

Comparison of simple potential functions for simulating liquid water

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2803%2900126-1

7 January 2021

10.1016/S1074-5521(03)00126-1

Identifiers

DOI

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3 December 2017

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