Generation of innovative anti-inflammatory and anti-arthritic glucocorticoid derivatives that release NO: the nitro-steroids (Q44503552)

3 December 2017

Generation of innovative anti-inflammatory and anti-arthritic glucocorticoid derivatives that release NO: the nitro-steroids (English)

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3 December 2017

4

R J Flower

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3 December 2017

1

M Perretti

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3 December 2017

M J Paul-Clark

2

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PubMed ID

12846443

3 December 2017

L Mancini

series ordinal

3

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3 December 2017

1 May 2003

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Digestive and Liver Disease

3 December 2017

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3 December 2017

35 Suppl 2

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3 December 2017

S41-8

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Physiological Functions of Glucocorticoids in Stress and Their Relation to Pharmacological Actions*

3 December 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Anti-inflammatory actions of glucocorticoids: molecular mechanisms

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https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

New twists in gene regulation by glucocorticoid receptor: is DNA binding dispensable?

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https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Molecular mechanisms of glucocorticosteroid actions.

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

A new hypothesis of modular glucocorticoid actions: steroid treatment of rheumatic diseases revisited

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Therapeutic benefit of a dissociated glucocorticoid and the relevance of in vitro separation of transrepression from transactivation activity

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Nitric oxide: an endogenous modulator of leukocyte adhesion

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https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Nitric oxide synthase inhibitors have opposite effects on acute inflammation depending on their route of administration.

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https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Nitric oxide inhibits numerous features of mast cell-induced inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Nitric oxide regulates nitric oxide synthase-2 gene expression by inhibiting NF-kappaB binding to DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

NO inhibits cytokine-induced iNOS expression and NF-kappaB activation by interfering with phosphorylation and degradation of IkappaB-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Biphasic regulation of NF-kappa B activity underlies the pro- and anti-inflammatory actions of nitric oxide.

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Anti-thrombotic effects of a nitric oxide-releasing, gastric-sparing aspirin derivative

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

21-NO-prednisolone is a novel nitric oxide-releasing derivative of prednisolone with enhanced anti-inflammatory properties

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Glucocorticoids decrease tissue mast cell number by reducing the production of the c-kit ligand, stem cell factor, by resident cells: in vitro and in vivo evidence in murine systems

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Potent antiarthritic properties of a glucocorticoid derivative, NCX-1015, in an experimental model of arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

NO-aspirin protects from T cell–mediated liver injury by inhibiting caspase-dependent processing of Th1-like cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

The Effect of Glucocorticoids on Joint Destruction in Rheumatoid Arthritis

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

The Michael Mason Prize Essay 1997. Nitric oxide and bone: what a gas!

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Expression and functional role of nitric oxide synthase in osteoblast-like cells

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Glucocorticoids inhibit bone resorption by isolated rat osteoclasts by enhancing apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Prevention of corticosteroid-induced bone loss with nitric oxide donor nitroglycerin in male rats

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

NO-steroids: potent anti-inflammatory drugs with bronchodilating activity in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Bidirectional regulation of osteoclast function by nitric oxide synthase isoforms

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Endothelial nitric oxide synthase gene-deficient mice demonstrate marked retardation in postnatal bone formation, reduced bone volume, and defects in osteoblast maturation and activity

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Low-dose prednisone induces rapid reversible axial bone loss in patients with rheumatoid arthritis. A randomized, controlled study

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

New developments in the pathogenesis and treatment of steroid-induced osteoporosis

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

Dexamethasone inhibits cytokine-induced intercellular adhesion molecule-1 up-regulation on endothelial cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2803%2900051-3

7 January 2021

10.1016/S1590-8658(03)00051-3

Identifiers

DOI

1 reference

3 December 2017

1 reference

PubMed ID

12846443