Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD. (Q44504087)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12847107%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD (English)

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5 November 2019

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1

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5 November 2019

author name string

Reiner Hitt

2

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5 November 2019

Sae-Hun Park

3

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5 November 2019

Peter M Deak

4

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5 November 2019

Zlatka Kostova

5

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5 November 2019

Dieter H Wolf

6

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5 November 2019

language of work or name

English

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publication date

7 July 2003

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Journal of Biological Chemistry

5 November 2019

published in

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5 November 2019

volume

278

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5 November 2019

page(s)

35903-35913

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5 November 2019

issue

38

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Retrograde protein translocation: ERADication of secretory proteins in health and disease

5 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

ER protein quality control and proteasome-mediated protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

The engagement of Sec61p in the ER dislocation process

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Membrane topology and function of Der3/Hrd1p as a ubiquitin-protein ligase (E3) involved in endoplasmic reticulum degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Degradation of unassembled Vph1p reveals novel aspects of the yeast ER quality control system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Retro-translocation of proteins from the endoplasmic reticulum into the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Disruption of six novel Saccharomyces cerevisiae genes reveals that YGL129c is necessary for growth in non-fermentable carbon sources, YGL128c for growth at low or high temperatures and YGL125w is implicated in the biosynthesis of methionine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

SBA1 encodes a yeast hsp90 cochaperone that is homologous to vertebrate p23 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

YDJ1p facilitates polypeptide translocation across different intracellular membranes by a conserved mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Functional interaction of cytosolic hsp70 and a DnaJ-related protein, Ydj1p, in protein translocation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Replacement of chromosome segments with altered DNA sequences constructed in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Mutational analysis of Hsp90 function: interactions with a steroid receptor and a protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

ER-golgi traffic is a prerequisite for efficient ER degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Endocytosis and vacuolar degradation of the plasma membrane-localized Pdr5 ATP-binding cassette multidrug transporter in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

N-Glycosylation affects endoplasmic reticulum degradation of a mutated derivative of carboxypeptidase yscY in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Degradation of misfolded endoplasmic reticulum glycoproteins in Saccharomyces cerevisiae is determined by a specific oligosaccharide structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Mnl1p, an alpha -mannosidase-like protein in yeast Saccharomyces cerevisiae, is required for endoplasmic reticulum-associated degradation of glycoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

A conserved ubiquitin ligase of the nuclear envelope/endoplasmic reticulum that functions in both ER-associated and Matalpha2 repressor degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Tyrosine phosphorylation regulates cell cycle-dependent nuclear localization of Cdc48p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Protein transport across the eukaryotic endoplasmic reticulum and bacterial inner membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

A novel SNARE complex implicated in vesicle fusion with the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Inhibition of endoplasmic reticulum (ER)-to-Golgi transport induces relocalization of binding protein (BiP) within the ER to form the BiP bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

An essential role for the substrate-binding region of Hsp40s in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Its substrate specificity characterizes the DnaJ co-chaperone as a scanning factor for the DnaK chaperone.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

The J-domain family and the recruitment of chaperone power

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Molecular chaperones: How J domains turn on Hsp70s

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

YPD, PombePD and WormPD: model organism volumes of the BioKnowledge library, an integrated resource for protein information

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Hsp90 & Co. - a holding for folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Global unfolding of a substrate protein by the Hsp100 chaperone ClpA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

A regulatory link between ER-associated protein degradation and the unfolded-protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

HRD gene dependence of endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Ubiquitin-mediated proteolysis of a short-lived regulatory protein depends on its cellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Molecular chaperones in the cytosol: from nascent chain to folded protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Endoproteolytic activity of the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Aut5/Cvt17p, a putative lipase essential for disintegration of autophagic bodies inside the vacuole

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Distinct domains within yeast Sec61p involved in post-translational translocation and protein dislocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

The requirement for molecular chaperones during endoplasmic reticulum-associated protein degradation demonstrates that protein export and import are mechanistically distinct

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Analysis of two mutated vacuolar proteins reveals a degradation pathway in the endoplasmic reticulum or a related compartment of yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Re-entering the translocon from the lumenal side of the endoplasmic reticulum. Studies on mutated carboxypeptidase yscY species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

Degradation of endoplasmic reticulum (ER) quality control substrates requires transport between the ER and Golgi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

J proteins catalytically activate Hsp70 molecules to trap a wide range of peptide sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M301080200

21 January 2018

Identifiers

DOI

10.1074/JBC.M301080200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12847107%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference