CDKN2A point mutations D153spl(c.457G>T) and IVS2+1G>T result in aberrant splice products affecting both p16INK4a and p14ARF. (Q44508752)

3 December 2017

title

CDKN2A point mutations D153spl(c.457G>T) and IVS2+1G>T result in aberrant splice products affecting both p16INK4a and p14ARF. (English)

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3 December 2017

Joni L Rutter

1

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Jeffery Struewing

object named as

Jeffery P Struewing

series ordinal

5

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Michael R Dávila

series ordinal

3

object named as

Michael R Dávila

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3 December 2017

4

Margaret A Tucker

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3 December 2017

2

Alisa M Goldstein

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3 December 2017

language of work or name

English

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publication date

1 July 2003

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3 December 2017

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3 December 2017

volume

22

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3 December 2017

issue

28

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3 December 2017

page(s)

4444-4448

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Genotype-Phenotype Relationships in U.S. Melanoma-Prone Families With CDKN2A and CDK4 Mutations

3 December 2017

cites work

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Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.

21 January 2018

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Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

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Differential expression of p16INK4a and p16beta transcripts in B-lymphoblastoid cells from members of hereditary melanoma families without CDKN2A exon mutations.

21 January 2018

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21 January 2018

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A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

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Cdkn2a, the cyclin-dependent kinase inhibitor encoding p16INK4a and p19ARF, is a candidate for the plasmacytoma susceptibility locus, Pctr1.

21 January 2018

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Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

21 January 2018

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CDKN2A germline splicing mutation affecting both p16ink4 and p14arf RNA processing in a melanoma/neurofibroma kindred

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/SJ.ONC.1206564

1 reference

3 December 2017

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