Topographical Assessment of Ethological and Dopamine Receptor Agonist-Induced Behavioral Phenotype in Mutants with Congenic DARPP-32 'Knockout'. (Q44515015)

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English	Topographical Assessment of Ethological and Dopamine Receptor Agonist-Induced Behavioral Phenotype in Mutants with Congenic DARPP-32 'Knockout'.	scientific article

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Europe PubMed Central

3 December 2017

Topographical Assessment of Ethological and Dopamine Receptor Agonist-Induced Behavioral Phenotype in Mutants with Congenic DARPP-32 'Knockout'. (English)

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3 December 2017

8

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Paul Greengard

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Europe PubMed Central

3 December 2017

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David T Croke

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author name string

Rachel E Nally

1

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Europe PubMed Central

3 December 2017

Fergal N McNamara

2

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Europe PubMed Central

3 December 2017

Jeremiah J Clifford

3

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Europe PubMed Central

3 December 2017

A Kinsella

4

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Europe PubMed Central

3 December 2017

Orna Tighe

5

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Europe PubMed Central

3 December 2017

Allen A Fienberg

7

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John L Waddington

9

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1 December 2003

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Neuropsychopharmacology

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3 December 2017

28

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12

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2055-2063

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Europe PubMed Central

3 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.npp.1300259

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Oestradiol increases phosphorylation of a dopamine- and cyclic AMP-regulated phosphoprotein (DARPP-32) in female rat brain

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Gender differences in dopaminergic function in striatum and nucleus accumbens

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Sex differences in striatal dopamine: in vivo microdialysis and behavioral studies.

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Essential fatty acids given from conception prevent topographies of motor deficit in a transgenic model of Huntington's disease

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Comparative, topographically-based evaluation of behavioural phenotype and specification of D(1)-like:D(2) interactions in a line of incipient congenic mice with D(2) dopamine receptor 'knockout'

1 reference

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Conservation of behavioural topography to dopamine D1-like receptor agonists in mutant mice lacking the D1A receptor implicates a D1-like receptor not coupled to adenylyl cyclase.

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Topographical evaluation of the phenotype of spontaneous behaviour in mice with targeted gene deletion of the D1A dopamine receptor: paradoxical elevation of grooming syntax.

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Topographical evaluation of behavioural phenotype in a line of mice with targeted gene deletion of the D2 dopamine receptor

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Genetics of mouse behavior: interactions with laboratory environment.

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Behavioral phenotypes of inbred mouse strains: implications and recommendations for molecular studies

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Genetic dissection of mouse exploratory behaviour

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Influence of the estrous cycle and estradiol on the behavioral effects of amphetamine and apomorphine in rats.

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Sex-linked behavioural differences in mice expressing a human insulin transgene in the medial habenula.

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DARPP-32: regulator of the efficacy of dopaminergic neurotransmission

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The effect of dopaminergic D1 receptor blockade during tetanization on the expression of long-term potentiation in the rat CA1 region in vitro

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Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

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Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade

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Distribution of protein phosphatase inhibitor-1 in brain and peripheral tissues of various species: comparison with DARPP-32.

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DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1

1 reference

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D1/D5 receptor agonists induce a protein synthesis-dependent late potentiation in the CA1 region of the hippocampus

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Apomorphine-induced behaviour during the oestrous cycle of the rat.

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Dopaminergic modulation of LTP induction in the dentate gyrus of intact brain.

1 reference

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Congenic D1A dopamine receptor mutants: ethologically based resolution of behavioural topography indicates genetic background as a determinant of knockout phenotype.

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Phenotypic, ethologically based resolution of spontaneous and D(2)-like vs D(1)-like agonist-induced behavioural topography in mice with congenic D(3) dopamine receptor "knockout".

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Complications associated with genetic background effects in research using knockout mice

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New insights into dopaminergic receptor function using antisense and genetically altered animals

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Behavioral effects of dopamine agonists across the estrous cycle in rats.

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Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors

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Phenotypic resolution of spontaneous and D1-like agonist-induced orofacial movement topographies in congenic dopamine D1A receptor 'knockout' mice

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The psychopharmacology-molecular biology interface: exploring the behavioural roles of dopamine receptor subtypes using targeted gene deletion ('knockout').

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Behavioural pharmacology of 'D-1-like' dopamine receptors: further subtyping, new pharmacological probes and interactions with 'D-2-like' receptors

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21 January 2018

Sex specific behavioural alterations in Mas-deficient mice.

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21 January 2018

The dopamine D3 receptor and autoreceptor preferring antagonists (+)-AJ76 and (+)-UH232; a microdialysis study

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Estrous cycle-dependent variation in amphetamine-induced behaviors and striatal dopamine release assessed with microdialysis

1 reference

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7 January 2021

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Heterogeneity of behavioural profile between three new putative selective D3 dopamine receptor antagonists using an ethologically based approach

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The DARPP-32 knockout mouse

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Locomotor activity in D2 dopamine receptor-deficient mice is determined by gene dosage, genetic background, and developmental adaptations

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Role of the adrenal gland and adrenal-mediated chemosignals in suppression of estrus in the house mouse: the lee-boot effect revisited

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Dopaminergic behaviour stereospecific promoted by the D1 agonist R-SK & F 38393 and selectively blocked by the D1 antagonist SCH 23390

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D1/D5 dopamine receptor activation increases the magnitude of early long-term potentiation at CA1 hippocampal synapses.

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Phosphodiesterase 1B knock-out mice exhibit exaggerated locomotor hyperactivity and DARPP-32 phosphorylation in response to dopamine agonists and display impaired spatial learning

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Phenotypic characterization of an alpha 4 neuronal nicotinic acetylcholine receptor subunit knock-out mouse

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Identifiers

10.1038/SJ.NPP.1300259

0 references

1 reference

Europe PubMed Central

3 December 2017

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