Oxidative DNA damage induced by photodegradation products of 3(')-azido-3(')-deoxythymidine (Q44534001)

3 December 2017

Oxidative DNA damage induced by photodegradation products of 3(')-azido-3(')-deoxythymidine (English)

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3 December 2017

Takuya Iwamoto

1

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3 December 2017

Yusuke Hiraku

2

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3 December 2017

Shinji Oikawa

3

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3 December 2017

Hideki Mizutani

4

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3 December 2017

Michio Kojima

5

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3 December 2017

Shosuke Kawanishi

6

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3 December 2017

language of work or name

English

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publication date

1 August 2003

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Archives of Biochemistry and Biophysics

3 December 2017

9

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based on heuristic

inferred from page(s)

published in

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3 December 2017

416

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3 December 2017

2

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3 December 2017

155-163

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Pharmacokinetic individualisation of zidovudine therapy. Current state of pharmacokinetic-pharmacodynamic relationships

3 December 2017

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Nonclinical toxicology studies with zidovudine: genetic toxicity tests and carcinogenicity bioassays in mice and rats

7 January 2021

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Transplacental effects of 3'-azido-2',3'-dideoxythymidine (AZT): tumorigenicity in mice and genotoxicity in mice and monkeys.

7 January 2021

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A transplacental carcinogenicity bioassay in CD-1 mice with zidovudine.

7 January 2021

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Multiorgan transplacental and neonatal carcinogenicity of 3'-azido-3'-deoxythymidine in mice

7 January 2021

1 reference

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Genotoxicity of 3'-azido-3'-deoxythymidine in the human lymphoblastoid cell line, TK6: relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT

7 January 2021

1 reference

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Relationships between DNA incorporation, mutant frequency, and loss of heterozygosity at the TK locus in human lymphoblastoid cells exposed to 3'-azido-3'-deoxythymidine

7 January 2021

1 reference

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Induction of the SOS response in Escherichia coli by azidothymidine and dideoxynucleosides

7 January 2021

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AZT treatment induces molecular and ultrastructural oxidative damage to muscle mitochondria. Prevention by antioxidant vitamins

7 January 2021

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Zidovudine (AZT) causes an oxidation of mitochondrial DNA in mouse liver

7 January 2021

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Oxidative DNA damage in fetal tissues after transplacental exposure to 3'-azido-3'-deoxythymidine (AZT)

7 January 2021

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Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA

7 January 2021

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Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

7 January 2021

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Purine bases, nucleosides, and nucleotides: aqueous solution redox chemistry and transformation reactions of their radical cations and e- and OH adducts

7 January 2021

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7 January 2021

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Superoxide formation and DNA damage induced by a fragrant furanone in the presence of copper(II)

7 January 2021

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A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

7 January 2021

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Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

7 January 2021

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57 Sequencing end-labeled DNA with base-specific chemical cleavages

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Formation of 8-hydroxyguanine moiety in cellular DNA by agents producing oxygen radicals and evidence for its repair.

7 January 2021

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Oxygen species in paraquat toxicity: the crypto-OH radical

7 January 2021

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Ethylene formation from methional

7 January 2021

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Free radical-induced double lesions in DNA.

7 January 2021

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Oxidative Nucleobase Modifications Leading to Strand Scission

7 January 2021

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Synthesis and characterization of oligodeoxynucleotides containing formamidopyrimidine lesions and nonhydrolyzable analogues

7 January 2021

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Novel substrates of Escherichia coli nth protein and its kinetics for excision of modified bases from DNA damaged by free radicals

7 January 2021

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Spontaneous and osmium tetroxide-induced mutagenesis in an Escherichia coli strain deficient in both endonuclease III and endonuclease VIII

7 January 2021

1 reference

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Generation of intracellular active oxygens in mouse FM3A cells by 3-hydroxyamino-1-methyl-5H-pyrido[4,3-b]indole, the activated Trp-P-2.

7 January 2021

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Mechanism of oxidative DNA damage induced by a heterocyclic amine, 2-amino-3,8-dimethylimidazo[4,5f]quinoxaline.

7 January 2021

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Distinct mechanisms of oxidative DNA damage by two metabolites of carcinogenic o-toluidine.

7 January 2021

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Metabolism of carcinogenic urethane to nitric oxide is involved in oxidative DNA damage

7 January 2021

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DNA degradation by the mixture of copper and catechol is caused by DNA-copper-hydroperoxo complexes, probably DNA-Cu(I)OOH

7 January 2021

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Modification of bases in DNA by copper ion-1,10-phenanthroline complexes

7 January 2021

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7 January 2021

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Hydroxyl radical is not the main reactive species involved in the degradation of DNA bases by copper in the presence of hydrogen peroxide

7 January 2021

1 reference

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Distinct mechanisms of guanine-specific DNA photodamage induced by nalidixic acid and fluoroquinolone antibacterials

7 January 2021

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Photosensitization of guanine-specific DNA damage by 2-phenylbenzimidazole and the sunscreen agent 2-phenylbenzimidazole-5-sulfonic acid

7 January 2021

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Ferritin stimulation of hydroxyl radical production by rat liver nuclei

7 January 2021

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The stimulus-secretion coupling of glucose-induced insulin release. XXXV. The links between metabolic and cationic events

7 January 2021

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Biological reduction of aromatic nitroso compounds: evidence for the involvement of superoxide anions

7 January 2021

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Clinical pharmacokinetics of zidovudine. An update

7 January 2021

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Metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by human cytochrome P4501A1, P4501A2 and P4501B1.

7 January 2021

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Interindividual variation in the metabolic activation of heterocyclic amines and their N-hydroxy derivatives in primary cultures of human mammary epithelial cells.

7 January 2021

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10.1016/S0003-9861(03)00316-3

7 January 2021

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DOI

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3 December 2017

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