Metabolic engineering of Escherichia coli for improved 6-deoxyerythronolide B production (Q44536620)

3 December 2017

Metabolic engineering of Escherichia coli for improved 6-deoxyerythronolide B production (English)

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S-[2-[3-[[(2R)-4-[[[(2R,3R,4S,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] hexadecanethioate

3 December 2017

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6-Deoxyerythronolide B

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9-{5-O-[{[(4-{[3-({2-[(2-Carboxypropanoyl)sulfanyl]ethyl}imino)-3-hydroxypropyl]imino}-3,4-dihydroxy-2,2-dimethylbutoxy)(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-3-O-phosphonopentofuranosyl}-9H-purin-6-amine

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Sumati Murli

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3 December 2017

Jonathan Kennedy

2

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3 December 2017

Linda C Dayem

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3 December 2017

John R Carney

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3 December 2017

James T Kealey

5

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3 December 2017

26 July 2003

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Journal of Industrial Microbiology & Biotechnology

3 December 2017

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3 December 2017

30

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3 December 2017

8

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3 December 2017

500-509

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Long-term and homogeneous regulation of the Escherichia coli araBAD promoter by use of a lactose transporter of relaxed specificity

3 December 2017

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12 December 2020

Discovering new enzymes and metabolic pathways: conversion of succinate to propionate by Escherichia coli.

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12 December 2020

Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli

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12 December 2020

Process and metabolic strategies for improved production of Escherichia coli-derived 6-deoxyerythronolide B.

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12 December 2020

Adenosylcobalamin-dependent methylmalonyl-CoA mutase from Propionibacterium shermanii. Active holoenzyme produced from Escherichia coli

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12 December 2020

Low-copy plasmids can perform as well as or better than high-copy plasmids for metabolic engineering of bacteria

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12 December 2020

Effect of copy number and mRNA processing and stabilization on transcript and protein levels from an engineered dual-gene operon

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12 December 2020

Metabolic engineering of a methylmalonyl-CoA mutase-epimerase pathway for complex polyketide biosynthesis in Escherichia coli

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12 December 2020

Enhanced production of heterologous macrolide aglycones by fed-batch cultivation of Streptomyces coelicolor

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12 December 2020

Complete nucleotide sequence and gene organization of the broad-host-range plasmid RSF1010.

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12 December 2020

Genetic and biochemical characterization of the alpha and beta components of a propionyl-CoA carboxylase complex of Streptomyces coelicolor A3(2).

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12 December 2020

Production of a polyketide natural product in nonpolyketide-producing prokaryotic and eukaryotic hosts

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12 December 2020

Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase

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12 December 2020

Controlling the metabolic flux through the carotenoid pathway using directed mRNA processing and stabilization

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12 December 2020

Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: application to open reading frame characterization

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12 December 2020

Homogeneous expression of the P(BAD) promoter in Escherichia coli by constitutive expression of the low-affinity high-capacity AraE transporter

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12 December 2020

A gene cluster encoding malonyl-CoA decarboxylase (MatA), malonyl-CoA synthetase (MatB) and a putative dicarboxylate carrier protein (MatC) in Rhizobium trifolii--cloning, sequencing, and expression of the enzymes in Escherichia coli

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12 December 2020

A multiplasmid approach to preparing large libraries of polyketides

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12 December 2020

Purification and characterization of methylmalonyl-CoA epimerase from Propionibacterium shermanii

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12 December 2020

The aadA gene of plasmid R100 confers resistance to spectinomycin and streptomycin in Myxococcus xanthus

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12 December 2020

Regulation of coenzyme A biosynthesis

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12 December 2020

10.1007/S10295-003-0073-X

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DOI

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3 December 2017

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