Pharmacological rescue of the 14CoS/14CoS mouse: hepatocyte apoptosis is likely caused by endogenous oxidative stress (Q44537856)

3 December 2017

Pharmacological rescue of the 14CoS/14CoS mouse: hepatocyte apoptosis is likely caused by endogenous oxidative stress (English)

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3 December 2017

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Matthew Z Dieter

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3 December 2017

Sarah L Freshwater

2

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3 December 2017

Marian L Miller

3

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3 December 2017

Howard G Shertzer

4

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3 December 2017

Timothy P Dalton

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3 December 2017

Daniel W Nebert

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3 December 2017

1 August 2003

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Free Radical Biology and Medicine

3 December 2017

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3 December 2017

35

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3 December 2017

4

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3 December 2017

351-367

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Genetic control of morphogenetic and biochemical differentiation: Lethal albino deletions in the mouse

3 December 2017

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Murine fumarylacetoacetate hydrolase (Fah) gene is disrupted by a neonatally lethal albino deletion that defines the hepatocyte-specific developmental regulation 1 (hsdr-1) locus

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Deficiency of an enzyme of tyrosine metabolism underlies altered gene expression in newborn liver of lethal albino mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Loss of fumarylacetoacetate hydrolase is responsible for the neonatal hepatic dysfunction phenotype of lethal albino mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Rescue of mice homozygous for lethal albino deletions: implications for an animal model for the human liver disease tyrosinemia type 1

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Marked increases in hepatic NAD(P)H:oxidoreductase gene transcription and mRNA levels correlated with a mouse chromosome 7 deletion

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

"Oxidative stress" response in liver of an untreated newborn mouse having a 1.2-centimorgan deletion on chromosome 7

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Regulation of gene expression by reactive oxygen

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Antioxidant response element

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Functional antioxidant responsive elements.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Treatment of hereditary tyrosinaemia type I by inhibition of 4-hydroxyphenylpyruvate dioxygenase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Tyrosinaemia type I and NTBC (2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione).

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

From toxicological problem to therapeutic use: the discovery of the mode of action of 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC), its toxicology and development as a drug

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Pharmacological correction of neonatal lethal hepatic dysfunction in a murine model of hereditary tyrosinaemia type I.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Glutathione monoethyl ester: high-performance liquid chromatographic analysis and direct preparation of the free base form

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor/antioxidant response element and metal response promoter elements

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Glutamate-cysteine ligase modifier subunit: mouse Gclm gene structure and regulation by agents that cause oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Temporalspatial patterns of expression of metallothionein-I and -III and other stress related genes in rat brain after kainic acid-induced seizures

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Nucleotide sequence of a full-length cDNA for mouse cytoskeletal beta-actin mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Determining glutathione and glutathione disulfide using the fluorescence probe o-phthalaldehyde

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Extrahepatic expression of NAD(P)H:menadione oxidoreductase, UDP glucuronosyltransferase-1A6, microsomal aldehyde dehydrogenase, and hepatic nuclear factor-1 alpha mRNAs in ch/ch and 14CoS/14CoS mice

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Cellular glutathione and thiols metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE)

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Heme oxygenase-1: function, regulation, and implication of a novel stress-inducible protein in oxidant-induced lung injury

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Differential regulation of gamma-glutamylcysteine synthetase heavy and light subunit gene expression

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Enzyme induction by L-buthionine (S,R)-sulfoximine in cultured mouse hepatoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Glutathione monoethyl ester: preparation, uptake by tissues, and conversion to glutathione.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

How does ascorbic acid prevent endothelial dysfunction?

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Effect of succinylacetone on heme and cytochrome P450 synthesis in hepatocyte culture

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Cytochrome P450 CYP1A1 accumulates in the cytosol of kidney and brain and is activated by heme

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Long-term therapy with NTBC and tyrosine-restricted diet in a murine model of hereditary tyrosinemia type I.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Hepatocellular response to chemical stress in CD-1 mice: induction of early genes and gamma-glutamylcysteine synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Complete rescue of lethal albino c14CoS mice by null mutation of 4-hydroxyphenylpyruvate dioxygenase and induction of apoptosis of hepatocytes in these mice by in vivo retrieval of the tyrosine catabolic pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Hepatocyte injury in tyrosinemia type 1 is induced by fumarylacetoacetate and is inhibited by caspase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Cyclin B-dependent kinase and caspase-1 activation precedes mitochondrial dysfunction in fumarylacetoacetate-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Ebselen induces apoptosis in HepG(2) cells through rapid depletion of intracellular thiols

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Disruption of redox homeostasis in tumor necrosis factor-induced apoptosis in a murine hepatocyte cell line

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Rescue of cells from apoptosis by inhibition of active GSH extrusion.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Inhibition of glutathione synthesis in the newborn rat: a model for endogenously produced oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Glutathione ester prevents buthionine sulfoximine-induced cataracts and lens epithelial cell damage

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Review: Oxidative stress and disease

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https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Excess dietary tyrosine and corneal lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Tissue distribution of 2-(2-nitro-4-trifluoromethylbenzoyl)cyclohexane-1-3-dione (NTBC): effect on enzymes involved in tyrosine catabolism and relevance to ocular toxicity in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

The effect of a low-protein diet and dietary supplementation of threonine on tyrosine and 2-(2-nitro-4-trifluoromethylbenzoyl) cyclohexane-1,3-dione-induced corneal lesions, the extent of tyrosinemia, and the activity of enzymes involved in tyrosine

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Tissue distribution of 2-(2-nitro-4-trifluoromethylbenzoyl)-cyclohexane-1,3-dione (NTBC) and its effect on enzymes involved in tyrosine catabolism in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Tyrosinemia type II: nine cases of ocular signs and symptoms

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

Corneal opacities associated with NTBC treatment.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2803%2900273-9

7 January 2021

10.1016/S0891-5849(03)00273-9

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3 December 2017

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