The anti-neoplastic and novel topoisomerase II-mediated cytotoxicity of neoamphimedine, a marine pyridoacridine. (Q44542018)

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6 November 2019

title

The anti-neoplastic and novel topoisomerase II-mediated cytotoxicity of neoamphimedine, a marine pyridoacridine (English)

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6 November 2019

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1

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6 November 2019

author name string

Sandra S Matsumoto

2

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6 November 2019

Joseph A Holden

3

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6 November 2019

Gisela P Concepción

4

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6 November 2019

Deniz Tasdemir

5

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6 November 2019

Chris M Ireland

6

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6 November 2019

Louis R Barrows

7

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6 November 2019

language of work or name

English

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publication date

1 August 2003

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6 November 2019

published in

Biochemical Pharmacology

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6 November 2019

volume

66

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6 November 2019

issue

3

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6 November 2019

page(s)

447-458

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Neoamphimedine: A New Pyridoacridine Topoisomerase II Inhibitor Which Catenates DNA

6 November 2019

cites work

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Pyridoacridine alkaloids from deep-water marine sponges of the family Pachastrellidae: structure revision of dercitin and related compounds and correlation with the kuanoniamines

7 January 2021

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Inhibition of topoisomerase II by the marine alkaloid ascididemin and induction of apoptosis in leukemia cells

7 January 2021

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Inhibition of topoisomerase II catalytic activity by pyridoacridine alkaloids from a Cystodytes sp. ascidian: a mechanism for the apparent intercalator-induced inhibition of topoisomerase II

7 January 2021

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The replication of kinetoplast DNA networks in Crithidia fasciculata

7 January 2021

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Makaluvamines vary in ability to induce dose-dependent DNA cleavage via topoisomerase II interaction

7 January 2021

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DNA topoisomerase-targeting antitumor drugs can be studied in yeast

7 January 2021

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Human DNA topoisomerase II: evaluation of enzyme activity in normal and neoplastic tissues

7 January 2021

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Intercalators promote the binding of RecA protein to double-stranded DNA

7 January 2021

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability

7 January 2021

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Differences in the topoisomerase I cleavage complexes formed by camptothecin and wakayin, a DNA-intercalating marine natural product

7 January 2021

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Double-stranded DNA cleavage/religation reaction of eukaryotic topoisomerase II: evidence for a nicked DNA intermediate

7 January 2021

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Knotted single-stranded DNA rings: a novel topological isomer of circular single-stranded DNA formed by treatment with Escherichia coli omega protein

7 January 2021

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E. coli and M. luteus DNA topoisomerase I can catalyze catenation or decatenation of double-stranded DNA rings

7 January 2021

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Catenation and knotting of duplex DNA by type 1 topoisomerases: a mechanistic parallel with type 2 topoisomerases

7 January 2021

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The absence of supercoiling in kinetoplast DNA minicircles.

7 January 2021

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The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II.

7 January 2021

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Topoisomerase poisons: harnessing the dark side of enzyme mechanism.

7 January 2021

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DNA topoisomerases: essential enzymes and lethal targets

7 January 2021

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The ATPase reaction cycle of yeast DNA topoisomerase II. Slow rates of ATP resynthesis and P(i) release

7 January 2021

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10.1016/S0006-2952(03)00209-0

7 January 2021

Identifiers

DOI

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6 November 2019

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