Pasteurella multocida toxin-induced activation of RhoA is mediated via two families of G{alpha} proteins, G{alpha}q and G{alpha}12/13. (Q44557194)

4 December 2017

Pasteurella multocida toxin-induced activation of RhoA is mediated via two families of G{alpha} proteins, G{alpha}q and G{alpha}12/13. (English)

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4 December 2017

Pasteurella multocida

object named as

Pasteurella multocida

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4

Klaus Aktories

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author name string

Joachim H C Orth

series ordinal

1

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4 December 2017

Simona Lang

series ordinal

2

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4 December 2017

Masatoshi Taniguchi

series ordinal

3

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4 December 2017

language of work or name

English

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publication date

1 September 2005

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Journal of Biological Chemistry

4 December 2017

7

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based on heuristic

inferred from page(s)

published in

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4 December 2017

280

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4 December 2017

44

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4 December 2017

36701-36707

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The pasteurella multocida toxin interacts with signalling pathways to perturb cell growth and differentiation.

4 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Pasteurella multocida toxin activates the inositol triphosphate signaling pathway in Xenopus oocytes via G(q)alpha-coupled phospholipase C-beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Pleiotropic effects of Pasteurella multocida toxin are mediated by Gq-dependent and -independent mechanisms. involvement of Gq but not G11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Action of Pasteurella multocida toxin depends on the helical domain of Galphaq

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Pasteurella multocida toxin, a potent intracellularly acting mitogen, induces p125FAK and paxillin tyrosine phosphorylation, actin stress fiber formation, and focal contact assembly in Swiss 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Pasteurella multocida toxin stimulates mitogenesis and cytoskeleton reorganization in Swiss 3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

G alpha 12 and G alpha 13 stimulate Rho-dependent stress fiber formation and focal adhesion assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

The role of Rho in G protein-coupled receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

RGS-containing RhoGEFs: the missing link between transforming G proteins and Rho?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Activation of RhoA by lysophosphatidic acid and Galpha12/13 subunits in neuronal cells: induction of neurite retraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Differential involvement of Galpha12 and Galpha13 in receptor-mediated stress fiber formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Receptor-dependent RhoA activation in G12/G13-deficient cells: genetic evidence for an involvement of Gq/G11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

The guanine nucleotide exchange factor p63RhoGEF, a specific link between Gq/11-coupled receptor signaling and RhoA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

G(q/11) is involved in insulin-stimulated inositol phosphoglycan putative mediator generation in rat liver membranes: co-localization of G(q/11) with the insulin receptor in membrane vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Dual actions of the Galpha(q) agonist Pasteurella multocida toxin to promote cardiomyocyte hypertrophy and enhance apoptosis susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Pasteurella multocida toxin as a tool for studying Gq signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Rapid and persistent desensitization of m3 muscarinic acetylcholine receptor-stimulated phospholipase D. Concomitant sensitization of phospholipase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Biological activity of a C-terminal fragment of Pasteurella multocida toxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

A novel Galphaq/11-selective inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Regulators of G-protein signalling: a novel protein family involved in timely deactivation and desensitization of signalling via heterotrimeric G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Pasteurella multocida toxin stimulates mitogen-activated protein kinase via G(q/11)-dependent transactivation of the epidermal growth factor receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

RhoA effector mutants reveal distinct effector pathways for cytoskeletal reorganization, SRF activation and transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

The small GTP-binding protein Rho links G protein-coupled receptors and Galpha12 to the serum response element and to cellular transformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Specific involvement of G proteins in regulation of serum response factor-mediated gene transcription by different receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

G protein selectivity is a determinant of RGS2 function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Cellular regulation of RGS proteins: modulators and integrators of G protein signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Role for G(12)/G(13) in agonist-induced vascular smooth muscle cell contraction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

Potent activation of RhoA by Galpha q and Gq-coupled receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M507203200

21 January 2018

Identifiers

DOI

10.1074/JBC.M507203200

1 reference

4 December 2017

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