Anthracycline secondary alcohol metabolite formation in human or rabbit heart: biochemical aspects and pharmacologic implications. (Q44578142)

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7 November 2019

title

Anthracycline secondary alcohol metabolite formation in human or rabbit heart: biochemical aspects and pharmacologic implications (English)

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7 November 2019

1

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7 November 2019

Giorgio Minotti

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7 November 2019

Andrea Silvestrini

4

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7 November 2019

Elisabetta Meucci

6

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7 November 2019

author name string

Giuseppe Ettore Martorana

3

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7 November 2019

Bruno Giardina

5

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language of work or name

English

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publication date

1 September 2003

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7 November 2019

published in

Biochemical Pharmacology

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7 November 2019

volume

66

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7 November 2019

issue

6

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7 November 2019

page(s)

989-998

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Doxorubicin-induced cardiomyopathy

7 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Free radical formation by antitumor quinones

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Role of iron in anthracycline cardiotoxicity: new tunes for an old song?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Clinical and pharmacologic investigation of the effects of alpha-tocopherol on adriamycin cardiotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Doxorubicin cardiotoxicity may be caused by its metabolite, doxorubicinol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

The aldo-keto reductase (AKR) superfamily: an update

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Forms and functions of human SDR enzymes

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1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Comparison of doxorubicin- and MEN 10755-induced long-term progressive cardiotoxicity in the rat

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1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

The secondary alcohol metabolite of doxorubicin irreversibly inactivates aconitase/iron regulatory protein-1 in cytosolic fractions from human myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

7 January 2021

Quantitation of protein

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

An improved HPLC method for therapeutic drug monitoring of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites in human plasma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

A highly specific aldose reductase inhibitor, ethyl 1-benzyl-3-hydroxy-2(5H)-oxopyrrole-4-carboxylate, and its congeners

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1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

The sorbinil trap: a predicted dead-end complex confirms the mechanism of aldose reductase inhibition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Mechanism of human aldehyde reductase: characterization of the active site pocket

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

The C-terminal loop of aldehyde reductase determines the substrate and inhibitor specificity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Doxorubicin metabolism and toxicity in human myocardium: role of cytoplasmic deglycosidation and carbonyl reduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Suppression of doxorubicin cardiotoxicity by overexpression of catalase in the heart of transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Inhibition of doxorubicin chronic toxicity in catalase-overexpressing transgenic mouse hearts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Cardioprotection with dexrazoxane for doxorubicin-containing therapy in advanced breast cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Secondary alcohol metabolites mediate iron delocalization in cytosolic fractions of myocardial biopsies exposed to anticancer anthracyclines. Novel linkage between anthracycline metabolism and iron-induced cardiotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

The effect of the flavonoids, quercetin, myricetin and epicatechin on the growth and enzyme activities of MCF7 human breast cancer cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

The effect of quercetin, a widely distributed flavonoid in food and drink, on cytosolic aldehyde dehydrogenase: a comparison with the effect of diethylstilboestrol.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Human pharmacokinetic characterization and in vitro study of the interaction between doxorubicin and paclitaxel in patients with breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Modulation of the in vitro cardiotoxicity of doxorubicin by flavonoids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

New synthetic flavonoids as potent protectors against doxorubicin-induced cardiotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Daunorubicin-induced cardiac injury in the rabbit: a role for daunorubicinol?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Role of daunorubicinol in daunorubicin-induced cardiotoxicity as evaluated with the model of isolated perfused rat heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Daunomycin-induced cardiotoxicity in children and adults. A review of 110 cases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Cytofluorescence localization and disposition of doxorubicin and doxorubicinol in rat cardiac tissue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Modeling the metabolism of idarubicin to idarubicinol in rat heart: effect of rutin and phenobarbital

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Inhibition of aldo-keto reductases by phenobarbital alters metabolism, pharmacokinetics and toxicity of doxorubicin in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

Heterogeneity of carbonyl reduction in subcellular fractions and different organs in rodents

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1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900442-8

10.1016/S0006-2952(03)00442-8

7 January 2021

Identifiers

DOI

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7 November 2019

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