In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes (Q44585453)
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scientific article published in October 2003
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English | In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes |
scientific article published in October 2003 |
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In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes (English)
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Amit S Kalgutkar
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Hang T Nguyen
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Alfin D N Vaz
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Anke Doan
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Deepak K Dalvie
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Dale G McLeod
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John C Murray
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1 October 2003
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