In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes (Q44585453)

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scientific article published in October 2003
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In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes
scientific article published in October 2003

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    In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes (English)
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    Amit S Kalgutkar
    Hang T Nguyen
    Alfin D N Vaz
    Anke Doan
    Deepak K Dalvie
    Dale G McLeod
    John C Murray
    1 October 2003
    1240-1250

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