5α-reduced C21 steroids are substrates for human cytochrome P450c17 (Q44604937)

reason for preferred rank

4 December 2017

5α-reduced C21 steroids are substrates for human cytochrome P450c17 (English)

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

17 March 2024

5alpha-reduced C21 steroids are substrates for human cytochrome P450c17 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14522586

17 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

17 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

17 March 2024

author name string

Manisha K. Gupta

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14522586

17 March 2024

Oleg L. Guryev

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14522586

17 March 2024

Richard J. Auchus

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14522586

17 March 2024

language of work or name

English

0 references

publication date

1 October 2003

1 reference

4 December 2017

15 October 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14522586

full work available at URL

17 March 2024

https://api.elsevier.com/content/article/PII:S0003986103003941?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

https://api.elsevier.com/content/article/PII:S0003986103003941?httpAccept=text/plain

17 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

Archives of Biochemistry and Biophysics

17 March 2024

published in

1 reference

4 December 2017

418

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4 December 2017

2

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4 December 2017

151-160

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Conservation of function between mammalian and plant steroid 5alpha-reductases

4 December 2017

2

1 reference

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The human corpus luteum secretes 5 alpha-pregnane-3,20-dione

17 March 2024

3

1 reference

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Studies on the biosynthesis in vivo and excretion of 16-unsaturated C19 steroids in the boar

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4

1 reference

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Opposing changes in 3alpha-hydroxysteroid dehydrogenase oxidative and reductive activities in rat leydig cells during pubertal development

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5

1 reference

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Changes in Leydig cell function during sexual maturation in the mouse

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7

1 reference

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Testicular steroid metabolism during development in the normal and hypogonadal mouse

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8

1 reference

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Influence of age and photoperiod on steroidogenic function of the testis in the golden hamster

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9

1 reference

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Prostate formation in a marsupial is mediated by the testicular androgen 5 alpha-androstane-3 alpha,17 beta-diol

17 March 2024

10

1 reference

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Serum 5alpha-androstane-3alpha,17beta-diol, androsterone, and testosterone concentrations in the male rat. Influence of age and gonadotropin stimulation

17 March 2024

11

1 reference

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Increased testicular 5α-androstane-3α, 17β-diol formation induced by treatment with [D-Ser(TBU)6, des-Gly-NH210]LHRH ethylamide in the rat

17 March 2024

12

1 reference

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Metabolic pathways for androstanediol formation in immature rat testis microsomes

17 March 2024

13

1 reference

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5alpha-androstane-3alpha,17beta-diol is formed in tammar wallaby pouch young testes by a pathway involving 5alpha-pregnane-3alpha,17alpha-diol-20-one as a key intermediate

17 March 2024

14

1 reference

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Purification and enzymatic properties of a recombinant fusion protein expressed in Escherichia coli containing the domains of bovine P450 17A and rat NADPH-P450 reductase.

17 March 2024

16

1 reference

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Deletion of steroid 5 alpha-reductase 2 gene in male pseudohermaphroditism

17 March 2024

17

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

The genetic and functional basis of isolated 17,20-lyase deficiency

17 March 2024

18

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

Yeast expression of animal and plant P450s in optimized redox environments

17 March 2024

19

1 reference

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Improved method for high efficiency transformation of intact yeast cells

17 March 2024

20

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer

17 March 2024

23

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

Interaction of apo-cytochrome b5 with cytochromes P4503A4 and P45017A: relevance of heme transfer reactions

17 March 2024

25

1 reference

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Preparation of 14,15-secoestra-1,3,5(10)-trien-15-ynes, inhibitors of estradiol dehydrogenase

17 March 2024

26

1 reference

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The enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21.

17 March 2024

27

1 reference

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Identification of the binding site on cytochrome P450 2B4 for cytochrome b5 and cytochrome P450 reductase.

17 March 2024

28

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway

17 March 2024

29

1 reference

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Modulation of the activity of human 17 alpha-hydroxylase-17,20-lyase (CYP17) by cytochrome b5: endocrinological and mechanistic implications

17 March 2024

31

1 reference

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The role of cytochrome b5 in the biosynthesis of androgens by human P450c17.

17 March 2024

33

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

Cytochrome b5 promotes the synthesis of delta 16-C19 steroids by homogeneous cytochrome P-450 C21 side-chain cleavage from pig testis

17 March 2024

34

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta

17 March 2024

35

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

Role reversal: new insights from new ligands for the xenobiotic receptor CAR.

17 March 2024

36

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

5 alpha-reduced androgens in the human fetal testis

17 March 2024

38

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

Molecular genetics of steroid 5 alpha-reductase 2 deficiency

17 March 2024

39

1 reference

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The effect of finasteride on the risk of acute urinary retention and the need for surgical treatment among men with benign prostatic hyperplasia. Finasteride Long-Term Efficacy and Safety Study Group

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1 reference

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Expression cloning and characterization of oxidative 17beta- and 3alpha-hydroxysteroid dehydrogenases from rat and human prostate

17 March 2024

43

1 reference

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Structure and function of 3 alpha-hydroxysteroid dehydrogenase

17 March 2024

44

1 reference

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Steroid hormone metabolites are barbiturate-like modulators of the GABA receptor

17 March 2024

45

1 reference

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Neurosteroids: molecular mechanisms of action and psychopharmacological significance.

17 March 2024

46

1 reference

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Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes

17 March 2024

48

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

Molecular defects of the androgen receptor

17 March 2024

49

1 reference

https://api.crossref.org/works/10.1016/J.ABB.2003.07.003

17 March 2024

Identifiers

1 reference

release_f4iyidvicrdzplliw7je2tmu5q

4 December 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/f4iyidvicrdzplliw7je2tmu5q

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference